Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Psmb11tm1(icre)Yout
Name:	proteasome (prosome, macropain) subunit, beta type, 11; targeted mutation 1, Yousuke Takahama
MGI ID:	MGI:5521208
Gene:	Psmb11  Location: Chr14:54862767-54867013 bp, + strand  Genetic Position: Chr14, 27.87 cM
Alliance:	Psmb11tm1(icre)Yout page

Germline Transmission:	Earliest citation of germline transmission: J:197387
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129 x C57BL/6

Allele Type:    Targeted (Null/knockout, Recombinase) Mutations:    Insertion, Intragenic deletion   Psmb11tm1(icre)Yout expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Psmb11 (MGI:1921152)   Mutation details: A codon improved cre cDNA and FRT flanked PGKK-neo cassette in reverse orientation were inserted in place of most of the sole exon. (J:197387)

Activity:	Tissue activity of this recombinase allele
Driver:	Psmb11 (mouse) Summary of all recombinase alleles driven by Psmb11. Alliance mouse Psmb11 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Psmb11 Mutation:	10 strains or lines available

Original:	J:197387 Ohigashi I, et al., Aire-expressing thymic medullary epithelial cells originate from beta5t-expressing progenitor cells. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9885-90
All:	1 reference(s)