Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Lrig1tm1(cre/ERT2)Kjen
Name:	leucine-rich repeats and immunoglobulin-like domains 1; targeted mutation 1, Kim B Jensen
MGI ID:	MGI:5520983
Synonyms:	Lrig1-EGFP, Lrig1::eGFP-IRES-CreERT2, Lrig1-EGFP-ires-CreERT2
Gene:	Lrig1  Location: Chr6:94581510-94677139 bp, - strand  Genetic Position: Chr6, 43.15 cM
Alliance:	Lrig1tm1(cre/ERT2)Kjen page

Germline Transmission:	Earliest citation of germline transmission: J:202041
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Lrig1tm1(cre/ERT2)Kjen expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Lrig1 (MGI:107935)   Mutation details: An EGFP-IRES-cre/ERT2 cassette was knocked into the translational start site in exon 1 of the endogenous Lrig1 gene in ES cells using homologous recombination. (J:202041)

Activity:	Tissue activity of this recombinase allele
Driver:	Lrig1 (mouse) Summary of all recombinase alleles driven by Lrig1. Comparative matrix view of recombinase activities Alliance mouse Lrig1 gene page

In Mice Carrying this Mutation:

29 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lrig1 Mutation:	49 strains or lines available

Original:	J:202041 Page ME, et al., The epidermis comprises autonomous compartments maintained by distinct stem cell populations. Cell Stem Cell. 2013 Oct 3;13(4):471-82
All:	12 reference(s)