Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lin28btm1.2Gqda
Name:	lin-28 homolog B; targeted mutation 1.2, George Q Daley
MGI ID:	MGI:5519954
Gene:	Lin28b  Location: Chr10:45252713-45362410 bp, - strand  Genetic Position: Chr10, 23.5 cM
Alliance:	Lin28btm1.2Gqda page

Germline Transmission:	Earliest citation of germline transmission: J:199720
Parent Cell Line:	v6.5 (ES Cell)
Strain of Origin:	(C57BL/6 x 129S4/SvJae)F1

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 2. FLP-mediated recombination removed the neomycin cassette. (J:101977, J:199720)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lin28b Mutation:	22 strains or lines available

Original:	J:199720 Shinoda G, et al., Fetal deficiency of lin28 programs life-long aberrations in growth and glucose metabolism. Stem Cells. 2013 Aug;31(8):1563-73
All:	5 reference(s)