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Tg(ACTA1-TRPC3)1Jmol
Transgene Detail
Summary
Symbol: Tg(ACTA1-TRPC3)1Jmol
Name: transgene insertion 1, Jeffery Molkentin
MGI ID: MGI:5516498
Synonyms: TRPC3 TG
Transgene: Tg(ACTA1-TRPC3)1Jmol  Location: unknown  
Alliance: Tg(ACTA1-TRPC3)1Jmol page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(ACTA1-TRPC3)1Jmol expresses 1 gene
 
Mutation detailsA modified human ACTA1 skeletal alpha-actin promoter (-2000 to +239) was used to drive muscle-specific expression of full-length human TRPC3 cDNA. Line 1 was generated. (J:154908)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:154908 Millay DP, et al., Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism. Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19023-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory