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Gene Expression Data
Assay Details
Assay
Reference: J:159669 Hajj GN, et al., Developmental expression of prion protein and its ligands stress-inducible protein 1 and vitronectin. J Comp Neurol. 2009 Nov 20;517(3):371-84
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5515371
Gene symbol: Prnp
Gene name: prion protein
Antibody: anti-PrPc
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2B/S2B: embryonic day 10.0 (more )
Note: Double labeled: green - Prnp; red/magenta - Stip1 (assay MGI:5515422).
Structure Level Pattern Image Note
TS16: future spinal cord Present 2C , 2B , S2C , S2B
TS16: notochord Strong S2C , S2B , 2B , 2C
Specimen 2F/S2F: embryonic day 10.0 (more )
Note: Double labeled: green - Prnp; red/magenta - Stip1 (assay MGI:5515422).
Structure Level Pattern Image Note
TS16: future spinal cord Present S2G , 2F , S2F , 2G
Specimen 2J/S2J: embryonic day 10.0 (more )
Note: Double labeled: green - Prnp; red/magenta - Vtn (assay MGI:5515423).
Structure Level Pattern Image Note
TS16: future spinal cord Present 2J , 2K , S2J , S2K
Specimen 2N/S2N: embryonic day 10.0 (more )
Note: Double labeled: green - Prnp; red/magenta - Gfap (assay MGI:5515424).
Structure Level Pattern Image Note
TS16: future spinal cord Present 2O , S2N , 2N , S2O Expressed in astrocytes.
Specimen 2Q/S2Q: embryonic day 10.0 (more )
Note: Double labeled: green - Prnp; red/magenta - Mapt (assay MGI:5515425).
Structure Level Pattern Image Note
TS16: future spinal cord Present Non-Uniform S2Q , 2S , S2S , 2Q Expressed in axons in the ventral portion. The dorsal part of the spinal cord showed nuclear abundance.
Specimen 3B/S3B: embryonic day 10.0 (more )
Note: Double labeled: green - Prnp; red/magenta - Stip1 (assay MGI:5515422).
Structure Level Pattern Image Note
TS16: dorsal root ganglion Present S3C , 3B , S3B , 3C
Specimen 3F/S3F: embryonic day 10.0 (more )
Note: Double labeled: green - Prnp; red/magenta - Stip1 (assay MGI:5515422).
Structure Level Pattern Image Note
TS16: dorsal root ganglion Present S3G , S3F , 3G , 3F
Specimen 3J/S3J: embryonic day 10.0 (more )
Note: Double labeled: green - Prnp; red/magenta - Vtn (assay MGI:5515423).
Structure Level Pattern Image Note
TS16: dorsal root ganglion Present 3K , S3K , S3J , 3J
Specimen 3N/S3N: embryonic day 10.0 (more )
Note: Double labeled: green - Prnp; red/magenta - Mapt (assay MGI:5515425).
Structure Level Pattern Image Note
TS16: dorsal root ganglion Present 3N , S3N , S3P , 3P Increased expression in growing axons.
Specimen 4K/S4K: embryonic day 10.0 (more )
Note: Double labeled: green - Prnp; red/magenta - Stip1 (assay MGI:5515422).
Structure Level Pattern Image Note
TS16: heart Strong S4L , S4K , 4K , 4L
Specimen 4N/S4N: embryonic day 10.0 (more )
Note: Double labeled: green - Prnp; red/magenta - Vtn (assay MGI:5515423).
Structure Level Pattern Image Note
TS16: heart Strong 4O , S4N , 4N , S4O
Specimen 6B/S5B: embryonic day 16.0 (more )
Note: Double labeled: green - Prnp; red/magenta - Stip1 (assay MGI:5515422).
Structure Level Pattern Image Note
TS24: neocortex Strong Regionally restricted S5B , 6B , 6C , S5C Expression is restricted to the cortical plate.
TS24: cortical plate Strong 6B , S5C , S5B , 6C
TS24: cerebral cortex intermediate zone Present Scattered S5C , 6B , 6C , S5B Could be newly differentiated neurons migrating from the subventricular zone to the cortical plate.
Specimen 6E/S5E: embryonic day 16.0 (more )
Note: Double labeled: green - Prnp; red/magenta - Stip1 (assay MGI:5515422).
Structure Level Pattern Image Note
TS24: dorsal root ganglion Strong 6F , 6E , S5E , S5F Expressed in cell bodies and growing neurites.
Specimen 6H/S5H: embryonic day 16.0 (more )
Note: Double labeled: green - Prnp; red/magenta - Stip1 (assay MGI:5515422).
Structure Level Pattern Image Note
TS24: heart Present S5H , 6H , S5I , 6I
Specimen 6K/S5K: embryonic day 16.0 (more )
Note: Double labeled: green - Prnp; red/magenta - Stip1 (assay MGI:5515422).
Structure Level Pattern Image Note
TS24: liver Present S5L , 6L , S5K , 6K
Specimen 6N/S5N: embryonic day 16.0 (more )
Note: Double labeled: green - Prnp; red/magenta - Stip1 (assay MGI:5515422).
Structure Level Pattern Image Note
TS24: lung mesenchyme Present S5O , 6O , 6N , S5N Expressed in the connective tissue.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory