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Gene Expression Data
Assay Details
Assay
Reference: J:56939 Miquerol L, et al., Multiple developmental roles of VEGF suggested by a LacZ-tagged allele. Dev Biol. 1999 Aug 15;212(2):307-22
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5512645
Gene symbol: Kdr
Gene name: kinase insert domain protein receptor
Reporter: lacZ
Direct Detection
Assay notes: Fixative was 0.2% glutaraldehyde, 2% paraformaldehyde for embryos <E10.5. Later stage embryos (>E10.5) were fixed 4% paraformaldehyde, embedded in Tissue Tek (OCT compound), frozen and cryosectioned.
Results
Specimen 3A: embryonic day 8.0; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS12: blood vessel Present Regionally restricted 3A Expression is in endothelial cells.

Specimen 3B: embryonic day 8.5; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS13: blood vessel Present Regionally restricted 3B Expression is in endothelial cells.

Specimen 3C: embryonic day 9.0; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS14: blood vessel Present Regionally restricted 3C Expression is in endothelial cells.

Specimen 4L: embryonic day 13.5; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS21: heart ventricle Strong 4L
TS21: heart atrium Weak 4L

Specimen 4M: embryonic day 13.5; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS21: endocardial tissue Present Regionally restricted 4M Expression is throughout the endocardium with the exception of the endocardial cushions.
TS21: outflow tract Present Regionally restricted 4M Expression is in the ednothelium.
TS21: endocardial cushion Absent 4M

Specimen 5E: embryonic day 13.5; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS21: blood vessel Strong Regionally restricted 5E Expression is in vessels surrounding the ureteric bud and not at the periphery of the kidney.
TS21: metanephros Strong Regionally restricted 5E Expression is in vessels surrounding the ureteric bud and not at the periphery of the kidney.

Specimen 5I: embryonic day 13.5; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS21: blood vessel Present Regionally restricted 5I Expression is in the vasculature.
TS21: lung Present Regionally restricted 5I Expression is in the vasculature.

Specimen 5K: embryonic day 13.5; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS22: blood vessel Present Regionally restricted 5K Expression is in the vasculature of the spleen.

Specimen 6E: embryonic day 13.5; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS21: adrenal gland Present Regionally restricted 6E Expression is in endothelial cells.
TS21: blood vessel Present Regionally restricted 6E Expression is in endothelial cells.

Specimen 6F: embryonic day 13.5; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS21: blood vessel Present Regionally restricted 6F Expression is in endothelial cells.
TS21: choroid plexus Present Regionally restricted 6F Expression is in endothelial cells.

Specimen 6G: embryonic day 13.5; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS21: developing vasculature of metanephros Present Regionally restricted 6G Expression is in endothelial cells.

Specimen 6H: embryonic day 13.5; Kdrtm1Jrt/Kdr+ (more )
Structure Level Pattern Image Note
TS21: blood vessel Present Regionally restricted 6H Expression is in endothelial cells.
TS21: stomach Present Regionally restricted 6H Expression is in endothelial cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory