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Trappc14tm2e(EUCOMM)Hmgu
Targeted Allele Detail
Summary
Symbol: Trappc14tm2e(EUCOMM)Hmgu
Name: trafficking protein particle complex 14; targeted mutation 2e, Helmholtz Zentrum Muenchen GmbH
MGI ID: MGI:5511431
Gene: Trappc14  Location: Chr5:138257918-138262295 bp, - strand  Genetic Position: Chr5, 77.0 cM
IMPC: Trappc14 gene page
Mutation
origin
Mutant Cell Lines:  HEPD0801_4_A01, HEPD0801_4_B01, HEPD0801_4_C01, HEPD0801_4_C02, HEPD0801_4_F02, HEPD0801_4_G02, HEPD0801_4_H02
Germline Transmission:  Unknown
Parent Cell Line:  JM8A3.N1.C2 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_Bact_P
 
Mutation detailsThe L1L2_Bact_P cassette was inserted at position 138260366 of Chromosome 5 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157065)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Trappc14 Mutation:  33 strains or lines available
References
Original:  J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory