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Tbl1xr1tm1.1Arte
Targeted Allele Detail
Summary
Symbol: Tbl1xr1tm1.1Arte
Name: transducin (beta)-like 1X-linked receptor 1; targeted mutation 1.1, TaconicArtemis
MGI ID: MGI:5511131
Gene: Tbl1xr1  Location: Chr3:22130816-22270758 bp, + strand  Genetic Position: Chr3, 7.58 cM
Alliance: Tbl1xr1tm1.1Arte page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:198124
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 5. An F3-flanked puromycin resistance cassette with a 3' loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the selection cassette and left exon 5 floxed. (J:198124)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbl1xr1 Mutation:  322 strains or lines available
References
Original:  J:198124 Rohm M, et al., Transcriptional cofactor TBLR1 controls lipid mobilization in white adipose tissue. Cell Metab. 2013 Apr 2;17(4):575-85
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory