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Gene Expression Data
Assay Details
Assay
Reference: J:72022 Esni F, et al., Dorsal pancreas agenesis in N-cadherin- deficient mice. Dev Biol. 2001 Oct 1;238(1):202-12
Assay type: RNA in situ
MGI Accession ID: MGI:5505583
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Probe: Isl1 probe20
Probe preparation: Antisense RNA
Results
Specimen 3A: embryonic day 9.5; Cdh2tm1Hyn/Cdh2+ (more )
Note: Double labeled: dark blue - Isl1; brown - Pdx1 (assay MGI:5505554).
Structure Level Pattern Image Note
TS15: foregut mesenchyme Present Regionally restricted 3A Expression was detected in lateral gut mesenchyme.
TS15: pancreas primordium Present 3A Expression was detected in presumptive endocrine cells within the endoderm and dorsal pancreatic mesenchyme.
Specimen 3D: embryonic day 9.5; Cdh2tm1Hyn/Cdh2tm1Hyn (more )
Note: Double labeled: dark blue - Isl1; brown - Pdx1 (assay MGI:5505554).
Structure Level Pattern Image Note
TS15: foregut mesenchyme Present Regionally restricted 3D Expression was unaffected in lateral gut mesenchyme.
TS15: pancreas primordium Present Regionally restricted 3D Expression was detected in the endoderm, but dorsal pancreatic mesenchymal cells were absent.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory