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Gene Expression Data
Assay Details
Assay
Reference: J:72022 Esni F, et al., Dorsal pancreas agenesis in N-cadherin- deficient mice. Dev Biol. 2001 Oct 1;238(1):202-12
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5505554
Gene symbol: Pdx1
Gene name: pancreatic and duodenal homeobox 1
Antibody: anti-IPF1
Results
Specimen 1B: embryonic day 9.5 (more )
Note: 18-20 somites.
Structure Level Pattern Image Note
TS14: foregut Present 1B
Specimen 1F: embryonic day 9.5 (more )
Note: 22 somites - late E9.5.
Structure Level Pattern Image Note
TS15: foregut Present 1F
Specimen 1H: embryonic day 9.5 (more )
Note: 22 somites - late E9.5.
Structure Level Pattern Image Note
TS15: foregut Present 1H
Specimen 2A: embryonic day 9.0; Cdh2tm1Hyn/Cdh2+ (more )
Structure Level Pattern Image Note
TS14: foregut-midgut junction Present Regionally restricted 2A Expression was detected in dorsal pancreatic endoderm.
Specimen 2B: embryonic day 9.0; Cdh2tm1Hyn/Cdh2tm1Hyn (more )
Structure Level Pattern Image Note
TS14: foregut-midgut junction Present Regionally restricted 2B Expression was detected in dorsal pancreatic endoderm at comparable levels to the heterozygous pancreas.
Specimen 2G +/-: embryonic day 9.5; Cdh2tm1Hyn/Cdh2+ (more )
Structure Level Pattern Image Note
TS15: pancreas primordium Present Regionally restricted 2G +/- Expression was detected in both dorsal and ventral pancreatic bud endoderm.
Specimen 2G -/-: embryonic day 9.5; Cdh2tm1Hyn/Cdh2tm1Hyn (more )
Structure Level Pattern Image Note
TS15: pancreas primordium Present Regionally restricted 2G -/- Expression was detected only in the ventral pancreatic bud endoderm in the mutant.
Specimen 2H: embryonic day 9.5; Cdh2tm1Hyn/Cdh2+ (more )
Structure Level Pattern Image Note
TS15: pancreas primordium Present Regionally restricted 2H Expression was detected in dorsal pancreatic bud.
Specimen 2J: embryonic day 9.5; Cdh2tm1Hyn/Cdh2tm1Hyn (more )
Structure Level Pattern Image Note
TS15: pancreas primordium Absent 2J The section through the dorsal pancreatic bud showed no staining.
Specimen 2L: embryonic day 9.5; Cdh2tm1Hyn/Cdh2+ (more )
Structure Level Pattern Image Note
TS15: pancreas primordium Present 2L Expression was detected in dorsal pancreatic bud.
Specimen 2N: embryonic day 9.5; Cdh2tm1Hyn/Cdh2tm1Hyn (more )
Structure Level Pattern Image Note
TS15: pancreas primordium Absent 2N The section through the dorsal pancreatic bud showed no staining.
Specimen 3A: embryonic day 9.5; Cdh2tm1Hyn/Cdh2+ (more )
Note: Double labeled: brown - Pdx1; dark blue - Isl1 (assay MGI:5505583).
Structure Level Pattern Image Note
TS15: pancreas primordium Present 3A Expression was detected in the dorsal and ventral pancreatic buds.
Specimen 3B: embryonic day 9.5; Cdh2tm1Hyn/Cdh2+ (more )
Note: Double labeled: brown - Pdx1; dark blue - Shh (assay MGI:5505611).
Structure Level Pattern Image Note
TS15: pancreas primordium Present Regionally restricted 3B Expression was detected in the ventral pancreatic bud.
Specimen 3C: embryonic day 9.5; Cdh2tm1Hyn/Cdh2+ (more )
Note: Double labeled: brown - Pdx1; dark blue - Cdh11 (assay MGI:5505613).
Structure Level Pattern Image Note
TS15: pancreas primordium Present 3C Expression was detected in the dorsal and ventral pancreatic buds.
Specimen 3D: embryonic day 9.5; Cdh2tm1Hyn/Cdh2tm1Hyn (more )
Note: Double labeled: brown - Pdx1; dark blue - Isl1 (assay MGI:5505583).
Structure Level Pattern Image Note
TS15: pancreas primordium Present Regionally restricted 3D Expression was detected in the ventral pancreatic bud.
Specimen 3E: embryonic day 9.5; Cdh2tm1Hyn/Cdh2tm1Hyn (more )
Note: Double labeled: brown - Pdx1; dark blue - Shh (assay MGI:5505611).
Structure Level Pattern Image Note
TS15: pancreas primordium Present 3E Expression was detected in the dorsal and ventral pancreatic buds.
Specimen 3F: embryonic day 9.5; Cdh2tm1Hyn/Cdh2tm1Hyn (more )
Note: Double labeled: brown - Pdx1; dark blue - Cdh11 (assay MGI:5505613).
Structure Level Pattern Image Note
TS15: pancreas primordium Present Regionally restricted 3F Expression was detected in the ventral pancreatic bud.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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