Gene Expression Data
Assay Details
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Assay
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Reference:
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J:85738
MacLean HE, et al., Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development. Dev Biol. 2003 Oct 1;262(1):51-63
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5505459
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Gene symbol:
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Trp53
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Gene name:
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transformation related protein 53
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Antibody:
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anti-p53 (FL-393, sc-6243)
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
5B +/+:
embryonic day 15.5
(more  )
Specimen
5B +/+:
(close  )
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Genetic Background:
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involves: BALB/c
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: tibia |
Present |
Regionally restricted |
5B +/+
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Expression was detected in osteoblasts of the bone collar, with low levels present in mature hypertrophic chondrocytes.
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Specimen
5B -/-:
(close )
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Genetic Background:
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involves: BALB/c
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Mutant Allele(s):
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Maftm1Glm/Maftm1Glm
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: tibia |
Present |
Regionally restricted |
5B -/-
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In the mutant, normal expression was detected in osteoblasts of the bone collar, with low levels present in mature hypertrophic chondrocytes.
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Analysis Tools
