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Gene Expression Data
Assay Details
Assay
Reference: J:82126 Schnabel CA, et al., Pbx1 regulates nephrogenesis and ureteric branching in the developing kidney. Dev Biol. 2003 Feb 15;254(2):262-76
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5505254
Gene symbol: Pbx1
Gene name: pre B cell leukemia homeobox 1
Antibody: anti-Pbx1b
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2A: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: metanephric mesenchyme Present 2A Expression is in the metanephric blastema and surrounding mesenchyme.
TS18: intraembryonic coelom Present Regionally restricted 2A Expression is in coelomic epithelium.
TS18: ureteric bud Absent 2A
Specimen 2B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: peripheral blastema Strong 2B Expression is in the metanephric blastema and surrounding mesenchyme.
TS19: mesenchyme of metanephros Strong 2B Expression is in the metanephric blastema and surrounding mesenchyme.
Specimen 2C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mesenchyme of metanephros Present Regionally restricted 2C Expression is thoughout the mesenchymal compartment in both the cortex and medulla.
Specimen 2D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mesenchyme of metanephros Present Regionally restricted 2D Expression is thoughout the mesenchymal compartment in both the cortex and medulla
Specimen 2E: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: nephrogenic zone Weak 2E Expression is in pretubular aggregates and cells undergoing epithelial conversion.
TS22: maturing glomerular tuft Present 2E
Specimen 2F: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: mesenchyme of metanephros Present 2F Higher levels are seen in stromal cells and lower levels are in the induced mesenchyme.
Specimen 2G: embryonic day 13.5; Pbx1tm1Mlc/Pbx1tm1Mlc (more )
Structure Level Pattern Image Note
TS21: metanephros Absent 2G
Specimen 2J: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: metanephric mesenchyme Present 2J
Specimen 5G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mesenchyme of metanephros Present 5G
Specimen 5H: embryonic day 13.5; Bmp7tm1Rob/Bmp7tm1Rob (more )
Structure Level Pattern Image Note
TS21: mesenchyme of metanephros Present 5H Expression in this mutant is the same as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory