Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Adgrl2tm1Sud
Name:	adhesion G protein-coupled receptor L2; targeted mutation 1, Thomas C Sudhof
MGI ID:	MGI:5503962
Synonyms:	Lphn2KI + neo
Gene:	Adgrl2  Location: Chr3:148521219-148696191 bp, - strand  Genetic Position: Chr3, 74.1 cM
Alliance:	Adgrl2tm1Sud page

Germline Transmission:	Earliest citation of germline transmission: J:246190
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S6/SvEvTac x C57BL/6J

Allele Type:    Targeted (Conditional ready, Reporter) Mutation:    Insertion   Mutation details: A targeting vector was designed to introduce a loxP site upstream of the first coding exon (exon 2). A segment carrying an F1 FRT site, FRT site, 1 kb of the mouse engrailed splice acceptor, 5 kb of Adgrl2 cDNA fused to mVenus green fluorescent protein, a polyA signal, FRT site, PGK-neomycin resistance cassette, tandem FRT and F1 FRT sites, and a loxP site were placed in intron 2. (J:246190)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adgrl2 Mutation:	81 strains or lines available

Original:	J:246190 Anderson GR, et al., Postsynaptic adhesion GPCR latrophilin-2 mediates target recognition in entorhinal-hippocampal synapse assembly. J Cell Biol. 2017 Nov 06;216(11):3831-3846
All:	3 reference(s)