About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:93141 Mattar P, et al., A screen for downstream effectors of Neurogenin2 in the embryonic neocortex. Dev Biol. 2004 Sep 15;273(2):373-89
Assay type: RNA in situ
MGI Accession ID: MGI:5502648
Gene symbol: Srgap2
Gene name: SLIT-ROBO Rho GTPase activating protein 2
Probe: IMAGE clone 5401611
Probe preparation: Antisense labelled with digoxigenin RNA
Assay notes: Authors refer to the gene as srGAP3, which is the human synonym for this gene (identified by the sequence id and IMAGE clone id).
Results
Specimen 3D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex ventricular layer Present 3D

Specimen 3E: embryonic day 13.5; Neurog2tm2Fgu/Neurog2tm2Fgu (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present Regionally restricted 3E Expression was down-regulated in cortical progenitors in the ventricular zone.
TS21: cortical preplate Present 3E Ectopic neurons were detected in the preplate.

Specimen 3F: embryonic day 13.5; Neurog1tm1And/Neurog1tm1And, Neurog2tm2Fgu/Neurog2tm2Fgu (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present Regionally restricted 3F Expression was down-regulated in cortical progenitors in the ventricular zone.
TS21: cortical preplate Present 3F Ectopic neurons were detected in the preplate.

Specimen 4E,E': embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cortical plate Present 4E' , 4E

Specimen 4F,F': embryonic day 15.5; Neurog2tm2Fgu/Neurog2tm2Fgu (more )
Structure Level Pattern Image Note
TS23: cortical plate Present Patchy 4F , 4F' Gaps in expression were noted in the mutant cortical plate.
TS23: cerebral cortex intermediate zone Present Patchy 4F' , 4F

Specimen 5G: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cerebral cortex Present Regionally restricted 5G Expression was detected in the subplate and cortical plate.

Specimen 5H: postnatal day 0; Neurog2tm2Fgu/Neurog2tm2Fgu (more )
Structure Level Pattern Image Note
TS27: cerebral cortex Present Regionally restricted 5H Expression was absent from the subplate in the mutant.

Specimen Supp. Table 1: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: telencephalon Present Regionally restricted Expression was detected in dorsal telencephalon.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory