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Gene Expression Data
Assay Details
Assay
Reference: J:70279 Garg V, et al., Tbx1, a DiGeorge syndrome candidate gene, is regulated by sonic hedgehog during pharyngeal arch development. Dev Biol. 2001 Jul 1;235(1):62-73
Assay type: RNA in situ
MGI Accession ID: MGI:5502568
Gene symbol: Tbx1
Gene name: T-box 1
Probe: Tbx1 cDNA6
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 3A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: head mesenchyme Present Regionally restricted 3A Expressed in the mesenchyme surrounding the neural tube.
TS15: branchial arch mesenchyme Present Regionally restricted 3A Expressed in the mesodermal core of pharyngeal arches.
Specimen 3B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 3rd branchial arch mesenchyme Present Regionally restricted 3B Expressed in the mesodermal core.
TS17: 4th branchial arch mesenchyme Present Regionally restricted 3B Expressed along the third aortic arch artery.
TS17: head mesenchyme Present 3B
TS17: trunk mesenchyme Present Regionally restricted 3B Expressed in the area surrounding the paired dorsal aortas.
Specimen 3C/D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: branchial arch endoderm Present 3C/D
TS17: branchial arch mesenchyme Present Regionally restricted 3C/D Expressed in the mesodermal core.
TS17: branchial arch mesenchyme derived from neural crest Absent 3C/D
Specimen 3E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: head mesenchyme Present 3E
TS19: sclerotome Present 3E
TS19: trunk mesenchyme Present Regionally restricted 3E Expressed in periaortic mesenchyme.
Specimen 3F/G: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: ear Present 3F/G
TS23: tooth Present 3F/G
TS23: vibrissa Present 3F/G
Specimen 4C/D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: branchial arch endoderm Present 4C/D
TS17: head mesenchyme Present 4C/D
TS17: otocyst epithelium Present 4C/D
TS17: branchial arch mesenchyme Present Regionally restricted 4C/D Expressed in the mesodermal core.
Specimen 4G/H: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: branchial arch endoderm Absent 4G/H
TS17: otocyst epithelium Present 4G/H Expression is not changed, compared with the wild type.
Specimen 4I/J: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch mesenchyme Present Regionally restricted 4I/J Expressed in the mesodermal core.
Specimen 4K/L: embryonic day 9.5; Hand2tm1Dsr/Hand2tm1Dsr (more )
Structure Level Pattern Image Note
TS15: branchial arch mesenchyme Present Regionally restricted 4K/L Expressed in the mesodermal core, same as the wild type.
Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: limb Present Regionally restricted Expressed in the proximal portion.
Specimen not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lung epithelium Present
TS23: trachea epithelium Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory