Camk2atm1e(EUCOMM)Hmgu
Targeted Allele Detail
|
Symbol: |
Camk2atm1e(EUCOMM)Hmgu |
Name: |
calcium/calmodulin-dependent protein kinase II alpha; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH |
MGI ID: |
MGI:5501533 |
Gene: |
Camk2a Location: Chr18:61058704-61121224 bp, + strand Genetic Position: Chr18, 34.41 cM
|
IMPC: |
Camk2a gene page |
|
Mutant Cell Lines: |
HEPD0895_6_A08, HEPD0895_6_C08, HEPD0895_6_D04, HEPD0895_6_E07, HEPD0895_6_F12, HEPD0895_6_G06, HEPD0895_6_H02 |
Germline Transmission: |
Unknown
|
Parent Cell Line: |
JM8A3.N1 (ES Cell)
|
Strain of Origin: |
C57BL/6N-Atm1Brd
|
Project Collection: |
EUCOMM
|
|
Allele Type: |
|
Targeted (Null/knockout, Reporter) |
Mutation: |
|
Insertion
Vector: L1L2_GT0_LF2A_LacZ_BetactP_neo
|
|
|
Mutation details: The L1L2_GT0_LF2A_LacZ_BetactP_neo cassette was inserted at position 61102638 of Chromosome 18 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157065)
|
|
|
|
Original: |
J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015; |
All: |
1 reference(s) |
|