Reporter:	lacZ
	Direct Detection

Structure	Level	Pattern	Image	Note
TS13: embryo	Present		1C cobl-LacZ	Expression pattern is identical to endogenous RNA expression.

Structure	Level	Pattern	Image	Note
TS13: neural tube	Present	Regionally restricted	3A	Expression is restricted to ventral domains.
TS13: future midbrain	Present	Regionally restricted	3A	Expression extends further laterally from the midline. Expression is broader than at more caudal levels.

Structure	Level	Pattern	Image	Note
TS13: future midbrain	Present	Regionally restricted	3B	Expression extends further laterally from the midline. Expression is broader than at more caudal levels.

Structure	Level	Pattern	Image	Note
TS13: neural tube floor plate	Present		3C	Expression is tightly restricted to the floorplate.

Structure	Level	Pattern	Image	Note
TS17: midbrain	Present	Regionally restricted	3D	Expression is downregulated in the posterior midbrain. Expression in the anterior is higher than in the posterior. It no longer appears expanded relative to other axial levels.
TS17: neural tube	Present	Regionally restricted	3D	Expression is restricted to ventral domains.

Structure	Level	Pattern	Image	Note
TS17: neural tube floor plate	Present		3E
TS17: notochord	Present		3E

Structure	Level	Pattern	Image	Note
TS19: neural tube	Present	Regionally restricted	3F	Expressed in the floorplate and two domains just lateral to the midline of the roofplate.
TS19: neural tube floor plate	Present		3F

Structure	Level	Pattern	Image	Note
TS20: spinal cord floor plate	Ambiguous		3G	Expression is greatly reduced, mostly absent.
TS20: spinal cord roof plate	Present		3G
TS20: spinal cord lateral wall	Present	Regionally restricted	3G	Expressed in the region of motor neuron development.

Structure	Level	Pattern	Image	Note
TS21: spinal cord roof plate	Present	Widespread	3H	Expression expands throughout the ventral half of the neural tube midline.

Structure	Level	Pattern	Image	Note
TS22: spinal cord mantle layer	Present	Widespread	3I	Expression increases throughout the ventral half of the spinal cord.
TS22: dorsal root ganglion	Present		3I
TS22: vertebral cartilage condensation	Present		3I

Structure	Level	Pattern	Image	Note
TS23: spinal cord mantle layer	Present	Widespread	3J	Expression increases throughout the ventral half of the spinal cord.
TS23: dorsal root ganglion	Present		3J
TS23: vertebral cartilage condensation	Present		3J

Structure	Level	Pattern	Image	Note
TS15: embryo	Present		7A

Structure	Level	Pattern	Image	Note
TS15: embryo	Present		7B

Structure	Level	Pattern	Image	Note
TS15: embryo	Present		7C

Structure	Level	Pattern	Image	Note
TS17: embryo	Present		7D

Structure	Level	Pattern	Image	Note
TS17: embryo	Present		7E

Structure	Level	Pattern	Image	Note
TS15: neural tube floor plate	Present		7G

Structure	Level	Pattern	Image	Note
TS15: neural tube floor plate	Present		7H	Expression is not greatly altered, compared with Cobl-LacZ homozygous.

Structure	Level	Pattern	Image	Note
TS15: embryo	Present		7I
TS15: neural tube floor plate	Present		7I

Structure	Level	Pattern	Image	Note
TS15: embryo	Present		7J
TS15: neural tube floor plate	Present		7J