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Gene Expression Data
Assay Details
Assay
Reference: J:54641 Minoo P, et al., Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryos. Dev Biol. 1999 May 1;209(1):60-71
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5499642
Gene symbol: Nkx2-1
Gene name: NK2 homeobox 1
Antibody: Anti-Nkx2.1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: foregut Present Regionally restricted 3A Expression was detected in a select group of endodermal cells surrounding the ventral wall of the anterior foregut. There was no staining in the dorsal wall of the anterior foregut.
Specimen 3B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: tracheal diverticulum Present 3B
TS15: esophageal region lumen Absent 3B
TS15: mesenchyme derived from splanchnopleure Absent 3B
Specimen 3C: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: lung epithelium Present 3C
Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: alveolus epithelium Present Regionally restricted Expression was detected in distal alveolar cells.
TS28: bronchiole epithelium Present Regionally restricted Expression was detected in proximal bronchiolar epithelial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory