Hoxd3 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:73281 Allan D, et al., RARgamma and Cdx1 Interactions in Vertebral Patterning. Dev Biol. 2001 Dec 1;240(1):46-60
Assay type:	RNA in situ
MGI Accession ID:	MGI:5499622
Gene symbol:	Hoxd3
Gene name:	homeobox D3

Probe:	Hoxd3 cDNA3
Probe preparation:	labelled with digoxigenin RNA

Results

Specimen wild-type: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: trunk paraxial mesenchyme	Present	Regionally restricted		Anterior boundary of expression is between somites 4 and 5.

Specimen Cdx1-/-: embryonic day 9.5; Cdx1^tm1Pgr/Cdx1^tm1Pgr (more

)

Structure	Level	Pattern	Image	Note
TS15: trunk paraxial mesenchyme	Present	Regionally restricted		Expression is shifted posteriorly in Cdx1 single mutant embryos relative to wild type controls.

Specimen Cdx1-/- Rarg-/-: embryonic day 9.5; Cdx1^tm1Pgr/Cdx1^tm1Pgr, Rarg^tm1Ipc/Rarg^tm1Ipc (more

)

Structure	Level	Pattern	Image	Note
TS15: trunk paraxial mesenchyme	Present	Regionally restricted		Authors state there was no further reduction of expression in Cdx1-Rarg double null mutants.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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