About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:59068 Pispa J, et al., Cusp patterning defect in Tabby mouse teeth and its partial rescue by FGF. Dev Biol. 1999 Dec 15;216(2):521-34
Assay type: RNA in situ
MGI Accession ID: MGI:5499547
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh cDNA16
Probe preparation: labelled with S35
Visualized with: Autoradiography
Results
Specimen 5c: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: lower jaw molar Present Regionally restricted 5c Expression in primary enamel knot.
TS22: primary enamel knot Present Regionally restricted 5c Expression in primary enamel knot.
Specimen 5d: embryonic day 14.0; EdaTa/? (more )
Note: the mutation is X-linked; the embryo could have been homozygous or hemizygous
Structure Level Pattern Image Note
TS22: lower jaw molar Weak Regionally restricted 5d Reduced area of expression compared to wild type.
TS22: primary enamel knot Weak Regionally restricted 5d Reduced area of expression compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory