Tg(Chat-EGFP/Rpl10a,Slc18a3)DW167Htz
Transgene Detail
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| Symbol: |
Tg(Chat-EGFP/Rpl10a,Slc18a3)DW167Htz |
| Name: |
transgene insertion DW167, Nathaniel Heintz |
| MGI ID: |
MGI:5496680 |
| Synonyms: |
ChAT-DW167, Tg(Chat-EGFP/Rpl10a)DW167Htz |
| Transgene: |
Tg(Chat-EGFP/Rpl10a,Slc18a3)DW167Htz Location: unknown
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| Alliance: |
Tg(Chat-EGFP/Rpl10a,Slc18a3)DW167Htz page
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: Transgenic mice were generated using modified BAC Rp23-431D9. EGFP fused to the ribosomal protein L10a was inserted in the BAC in such a way that expression was driven by Chat. The BAC used to generate the construct includes the vesicular acetylcholine transporter gene (Slc18a3 or VAChT). Slc18a3 is located in the intron between the first and second exons of the Chat gene and is under the control of the Chat promoter. VAChT protein is overexpressed in the hippocampus and brainstem.
(J:150403)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:150403 Doyle JP, et al., Application of a translational profiling approach for the comparative analysis of CNS cell types. Cell. 2008 Nov 14;135(4):749-62 |
| All: |
23 reference(s) |
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Analysis Tools
