Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Chat-EGFP/Rpl10a,Slc18a3)DW167Htz
Name:	transgene insertion DW167, Nathaniel Heintz
MGI ID:	MGI:5496680
Synonyms:	ChAT-DW167, Tg(Chat-EGFP/Rpl10a)DW167Htz
Transgene:	Tg(Chat-EGFP/Rpl10a,Slc18a3)DW167Htz  Location: unknown
Alliance:	Tg(Chat-EGFP/Rpl10a,Slc18a3)DW167Htz page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Reporter) Mutation:    Insertion   Mutation details: Transgenic mice were generated using modified BAC Rp23-431D9. EGFP fused to the ribosomal protein L10a was inserted in the BAC in such a way that expression was driven by Chat. The BAC used to generate the construct includes the vesicular acetylcholine transporter gene (Slc18a3 or VAChT). Slc18a3 is located in the intron between the first and second exons of the Chat gene and is under the control of the Chat promoter. VAChT protein is overexpressed in the hippocampus and brainstem. (J:150403)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:150403 Doyle JP, et al., Application of a translational profiling approach for the comparative analysis of CNS cell types. Cell. 2008 Nov 14;135(4):749-62
All:	19 reference(s)