Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Homer1tm1Kino
Name:	homer scaffolding protein 1; targeted mutation 1, Kaoru Inokuchi
MGI ID:	MGI:5496433
Synonyms:	Vesl-1L-
Gene:	Homer1  Location: Chr13:93436143-93541637 bp, + strand  Genetic Position: Chr13, 47.83 cM
Alliance:	Homer1tm1Kino page

Germline Transmission:	Earliest citation of germline transmission: J:198336
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted Mutations:    Insertion, Intragenic deletion   Mutation details: The portion coding the C-terminal 11 amino acids was replaced by a cDNA encoding the long form-specific C-terminal amino acid (exons 7 through 11) followed by a polyadenylation sequence and a neomycin resistance cassette. Northern blot analysis confirmed transcript expression of the long isoform and not the short isoform. (J:198336)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Homer1 Mutation:	24 strains or lines available

Original:	J:198336 Inoue N, et al., Requirement of the immediate early gene vesl-1S/homer-1a for fear memory formation. Mol Brain. 2009;2:7
All:	2 reference(s)