Gene Expression Data
Assay Details
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Assay
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Reference:
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J:110707
Pattyn A, et al., Delays in neuronal differentiation in Mash1/Ascl1 mutants. Dev Biol. 2006 Jul 1;295(1):67-75
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5495269
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Gene symbol:
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Tlx3
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Gene name:
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T cell leukemia, homeobox 3
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Probe:
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Tlx3 probe1
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Probe preparation:
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labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
2C WT:
embryonic day 10.5
(more  )
Specimen
2C WT:
(close  )
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Genetic Background:
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involves: 129
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: hindbrain |
Present |
Regionally restricted |
2C WT
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Expression in nucleus of solitary tract (nTS) and area postrema (ap).
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Specimen
2C Mash1-/-:
(close )
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Genetic Background:
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involves: 129
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Mutant Allele(s):
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Ascl1tm1And/Ascl1tm1And
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: hindbrain |
Absent |
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2C Mash1-/-
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Authors state that nucleus of solitary tract precursors (nTSp) are not detected. Hindbrain dl5 neurons are also absent.
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Specimen
2F WT:
embryonic day 11.5
(more )
Specimen
2F WT:
(close )
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Genetic Background:
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involves: 129
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: hindbrain |
Present |
Regionally restricted |
2F WT
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Expression in nucleus of solitary tract (nTS) and area postrema (ap).
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Specimen
2F Mash1-/-:
(close )
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Genetic Background:
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involves: 129
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Mutant Allele(s):
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Ascl1tm1And/Ascl1tm1And
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: hindbrain |
Present |
Regionally restricted |
2F Mash1-/-
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Few nucleus of solitary tract precursors (nTSp) are detectable, but no dl5 neurons.
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Analysis Tools