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Cxcl14tm1Rih
Targeted Allele Detail
Summary
Symbol: Cxcl14tm1Rih
Name: C-X-C motif chemokine ligand 14; targeted mutation 1, Ryu-Ichiro Hata
MGI ID: MGI:5494299
Synonyms: BMAC floxed
Gene: Cxcl14  Location: Chr13:56436456-56444364 bp, - strand  Genetic Position: Chr13, 30.06 cM
Alliance: Cxcl14tm1Rih page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:197672
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 2, which encodes the chemokine CXC motif of the encoded protein. A second loxP site was inserted downstream of exon 2 and a neomycin resistance gene (Neo) fused to the phosphoglycerokinase (PGK) promoter (PGK-Neo) was inserted upstream of the loxP site. (J:197672)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cxcl14 Mutation:  17 strains or lines available
References
Original:  J:197672 Yajima N, et al., Production of conditional knockout mice for chemokine BMAC/cxcl14 gene by Cre/loxP system. Inflamm Regen. 2010;30(6):536-541
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory