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Gene Expression Data
Assay Details
Assay
Reference: J:171806 Young B, et al., Indian and sonic hedgehogs regulate synchondrosis growth plate and cranial base development and function. Dev Biol. 2006 Nov 1;299(1):272-82
Assay type: RNA in situ
MGI Accession ID: MGI:5493149
Gene symbol: H4c3
Gene name: H4 clustered histone 3
Probe: H4C cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cranial synchondrosis Present Regionally restricted 2A Expression was detected in proliferating chondrocytes in the proliferative zone in intrasphenoidal synchondroses. Scattered proliferating chondrocytes were also seen the in reserve zone, but not in the hypertrophic zone.

Specimen 2B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cranial synchondrosis Present Regionally restricted 2B Expression was detected in proliferating chondrocytes in the proliferative zone in spheno-occipital synchondroses. Scattered proliferating chondrocytes were also seen the in reserve zone, but not in the hypertrophic zone.

Specimen 2C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cranial synchondrosis Present Regionally restricted 2C Expression was detected in proliferating chondrocytes in the proliferative zone in intrasphenoidal synchondroses. Scattered proliferating chondrocytes were also seen the in reserve zone, but not in the hypertrophic zone.

Specimen 2D: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cranial synchondrosis Present Regionally restricted 2D Expression was detected in proliferating chondrocytes in the proliferative zone in spheno-occipital synchondroses. Scattered proliferating chondrocytes were also seen the in reserve zone, but not in the hypertrophic zone.

Specimen 2E: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cranial synchondrosis Present Regionally restricted 2E Expression was detected in proliferating chondrocytes in the proliferative zone in intrasphenoidal synchondroses. Proliferating chondrocytes in the reserve zone had decreased by P0. No positive cells were in the hypertrophic zone.

Specimen 2F: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cranial synchondrosis Present Regionally restricted 2F Expression was detected in proliferating chondrocytes in the proliferative zone in spheno-occipital synchondroses. Proliferating chondrocytes in the reserve zone had decreased by P0. No positive cells were in the hypertrophic zone.

Specimen 2G: embryonic day 15.5; Ihhtm1Amc/Ihhtm1Amc (more )
Structure Level Pattern Image Note
TS23: cranial synchondrosis Trace Regionally restricted 2G The number of proliferating chondrocytes was extremely low in the intrasphenoidal synchondroses.

Specimen 2H: embryonic day 15.5; Ihhtm1Amc/Ihhtm1Amc (more )
Structure Level Pattern Image Note
TS23: cranial synchondrosis Trace Regionally restricted 2H The number of proliferating chondrocytes was extremely low in the spheno-occipital synchondroses.

Specimen 2I: embryonic day 17.5; Ihhtm1Amc/Ihhtm1Amc (more )
Structure Level Pattern Image Note
TS25: cranial synchondrosis Trace Regionally restricted 2I The number of proliferating chondrocytes was extremely low in the intrasphenoidal synchondroses.

Specimen 2J: embryonic day 17.5; Ihhtm1Amc/Ihhtm1Amc (more )
Structure Level Pattern Image Note
TS25: cranial synchondrosis Trace Regionally restricted 2J The number of proliferating chondrocytes was extremely low in the spheno-occipital synchondroses.

Specimen 2K: postnatal day 0; Ihhtm1Amc/Ihhtm1Amc (more )
Structure Level Pattern Image Note
TS27: cranial synchondrosis Trace Regionally restricted 2K The number of proliferating chondrocytes was extremely low in the intrasphenoidal synchondroses.

Specimen 2L: postnatal day 0; Ihhtm1Amc/Ihhtm1Amc (more )
Structure Level Pattern Image Note
TS27: cranial synchondrosis Trace Regionally restricted 2L The number of proliferating chondrocytes was extremely low in the spheno-occipital synchondroses.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory