Gsc In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:77801 Soo K, et al., Twist function is required for the morphogenesis of the cephalic neural tube and the differentiation of the cranial neural crest cells in the mouse embryo. Dev Biol. 2002 Jul 15;247(2):251-70
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:5491953
Gene symbol:	Gsc
Gene name:	goosecoid homeobox

Reporter:	lacZ
	Direct Detection

Results

Specimen not shown +/+: embryonic day 9.5; Gsc^tm2Bhr/Gsc⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: 1st branchial arch mandibular component	Present	Regionally restricted		Expression was detected in the distal region of the first branchial arch (the prospective mandiblular rami and symphysis).
TS15: 2nd branchial arch	Present	Regionally restricted		Expression was dectected in the second arch around the first branchial groove.

Specimen not shown -/- 1: embryonic day 9.5; Gsc^tm2Bhr/Gsc⁺, Twist1^tm1Bhr/Twist1^tm1Bhr (more

)

Structure	Level	Pattern	Image	Note
TS15: branchial arch	Absent			Expression was completely absent in 4 embryos.

Specimen not shown -/- 2: embryonic day 9.5; Gsc^tm2Bhr/Gsc⁺, Twist1^tm1Bhr/Twist1^tm1Bhr (more

)

Structure	Level	Pattern	Image	Note
TS15: branchial arch	Weak			In 5 embryos expression was detected at a much-reduced level.

8A +/+ ©

Specimen 8A +/+: embryonic day 10.5; Gsc^tm2Bhr/Gsc⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: 1st branchial arch mandibular component	Present	Regionally restricted	8A +/+	Expression was detected in the distal region of the first branchial arch (the prospective mandiblular rami and symphysis).
TS17: 2nd branchial arch	Present	Regionally restricted	8A +/+	Expression was dectected in the second arch around the first branchial groove.

8A -/- ©

Specimen 8A -/-: embryonic day 10.5; Gsc^tm2Bhr/Gsc⁺, Twist1^tm1Bhr/Twist1^tm1Bhr (more

)

Structure	Level	Pattern	Image	Note
TS17: branchial arch	Absent		8A -/-	Expression was completely absent in 8 embryos.

Specimen not shown -/- E10.5: embryonic day 10.5; Gsc^tm2Bhr/Gsc⁺, Twist1^tm1Bhr/Twist1^tm1Bhr (more

)

Structure	Level	Pattern	Image	Note
TS17: branchial arch	Weak			In 3 embryos expression was detected at a much-reduced level.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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