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Gene Expression Data
Assay Details
Assay
Reference: J:63184 Lovicu FJ, et al., Expression of crim1 during murine ocular development. Mech Dev. 2000 Jun;94(1-2):261-5
Assay type: RNA in situ
MGI Accession ID: MGI:5491888
Gene symbol: Crim1
Gene name: cysteine rich transmembrane BMP regulator 1
Probe: Crim1 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1A/B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: surface ectoderm Present Regionally restricted 1A/B Expression is in the head ectoderm near the optic vesicle.
TS15: lens placode Present 1A/B

Specimen 1C/D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lens pit Strong 1C/D
TS17: eye Present Regionally restricted 1C/D Expression is in the corneal epithelium.
TS17: optic cup outer layer Present 1C/D

Specimen 2A/B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lens vesicle Strong 2A/B
TS19: cornea epithelium Present 2A/B
TS19: pigmented retinal epithelium Present 2A/B
TS19: eye Present Regionally restricted 2A/B Expression is in conjunctiva.

Specimen 2C/D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lens vesicle Strong 2C/D
TS20: cornea epithelium Present 2C/D
TS20: pigmented retinal epithelium Present 2C/D
TS20: eye Present Regionally restricted 2C/D Expression is in conjunctiva.

Specimen 2E/F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lens epithelium Strong 2E/F
TS21: lens fiber Strong 2E/F
TS21: pigmented retinal epithelium Strong Regionally restricted 2E/F Expression is in the posterior region.
TS21: eye Present Regionally restricted 2E/F Expression is in conjunctiva.
TS21: cornea epithelium Present 2E/F

Specimen 3A/B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: conjunctival sac Strong 3A/B
TS22: cornea epithelium Strong 3A/B
TS22: lens fiber Present 3A/B Expression in the embryonic nucleus of the lens is reduced.
TS22: pigmented retinal epithelium Strong Regionally restricted 3A/B Expression is in the posterior region.

Specimen 3C/D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: conjunctival sac Strong 3C/D
TS23: cornea epithelium Strong 3C/D
TS23: cornea Present Regionally restricted 3C/D Corneal endothelium.
TS23: eye Present Regionally restricted 3C/D Expression is at the rim of the optic cup.
TS23: neural retina Present Regionally restricted 3C/D Expression is in the ganglion cell layer.
TS23: pigmented retinal epithelium Present Regionally restricted 3C/D Expression extends more anteriorly and is strong in the developing ciliary and iridial retinae.

Specimen 3E/F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lens epithelium Strong 3E/F
TS26: lens fiber Strong 3E/F
TS26: neural retina Present Regionally restricted 3E/F In the layer of blood vessels aligned along the inner limiting membrane of the neural retina, ganglion cell layer, and the innermost region of the differentiating neuroblast layer.
TS26: conjunctival sac Present 3E/F
TS26: cornea endothelium Present 3E/F
TS26: cornea epithelium Present 3E/F
TS26: pigmented retinal epithelium Present 3E/F

Specimen 4A/B: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: lens epithelium Strong 4A/B

Specimen 4C/D: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: lens Present Regionally restricted 4C/D Expression is in nuclei of the lens bow, up about the region of early nuclear condensation in the cortical fiber cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory