Tg(Gt(ROSA)26Sor-Fucci2)#Sia
Transgene Detail
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| Symbol: |
Tg(Gt(ROSA)26Sor-Fucci2)#Sia |
| Name: |
transgene insertion, Shinichi Aizawa |
| MGI ID: |
MGI:5491593 |
| Synonyms: |
R26p-Fucci2, Tg(Gt(ROSA)26Sor-mCherry/CDT1,-mVenus/GMNN)#Sia |
| Transgene: |
Tg(Gt(ROSA)26Sor-Fucci2)#Sia Location: unknown
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| Alliance: |
Tg(Gt(ROSA)26Sor-Fucci2)#Sia page
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| Strain of Origin: |
(C57BL/6N x DBA/2N)F1
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: The fluorescent ubiquitylation-based cell cycle indicator (Fucci2) is composed of two transgenes in which the mouse promoter driving ubiquitous expression of two fusion reporters. The mCherry and the ubiquitylation domains of human CDT1 fusion accumulates in the nuclei at G1 phase. The mVenus and the ubiquitylation domains of human GMNN fusion accumulates in the nuclei at S/G2/M phases. Chicken hypersensitive site 4 (cHS4) transcriptional insulator sequences flank the two transgenes. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:196795)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:196795 Abe T, et al., Visualization of cell cycle in mouse embryos with Fucci2 reporter directed by Rosa26 promoter. Development. 2013 Jan 1;140(1):237-46 |
| All: |
17 reference(s) |
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Analysis Tools
