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Gene Expression Data
Assay Details
Assay
Reference: J:77801 Soo K, et al., Twist function is required for the morphogenesis of the cephalic neural tube and the differentiation of the cranial neural crest cells in the mouse embryo. Dev Biol. 2002 Jul 15;247(2):251-70
Assay type: RNA in situ
MGI Accession ID: MGI:5491308
Gene symbol: Six3
Gene name: sine oculis-related homeobox 3
Probe: Six3 probe12
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A +/+: embryonic day 8.5 (more )
Note: Also stained for En1 (assay MGI:5491314), whose expression is indicated by a red arrow.
Structure Level Pattern Image Note
TS13: future prosencephalon Present Regionally restricted 2A +/+ Expression was detected in ventral telencephalon.
Specimen 2A -/-: embryonic day 8.5; Twist1tm1Bhr/Twist1tm1Bhr (more )
Note: Also stained for En1 (assay MGI:5491314), whose expression is indicated by a red arrow.
Structure Level Pattern Image Note
TS13: future spinal cord neural plate Present Regionally restricted 2A -/- Expression was detected in the rostral-most medial (prospective ventral) region of the open anterior neural plate. Expression was in a slightly expanded domain.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory