Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ano6tm1Avor
Name:	anoctamin 6; targeted mutation 1, Andrea Vortkamp
MGI ID:	MGI:5486205
Gene:	Ano6  Location: Chr15:95688724-95872632 bp, + strand  Genetic Position: Chr15, 50.66 cM
Alliance:	Ano6tm1Avor page

Germline Transmission:	Earliest citation of germline transmission: J:195901
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: A lacZ and neo cassette replaced exon 1. RT-PCR confirmed the absence of transcript expression in the osteoblasts. (J:195901)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	14 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ano6 Mutation:	81 strains or lines available

Original:	J:195901 Ehlen H, Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues. J Bone Miner Res. 2013;28(2):246-59
All:	6 reference(s)