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Gene Expression Data
Assay Details
Assay
Reference: J:169680 Karni-Schmidt O, et al., Distinct Expression Profiles of p63 Variants during Urothelial Development and Bladder Cancer Progression. Am J Pathol. 2011 Mar;178(3):1350-60
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5476985
Gene symbol: Trp63
Gene name: transformation related protein 63
Antibody: 4A4
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 2B E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: urothelium of bladder Present 2B E16.5 p63 (4A4) The TA isoforms were detected as early as E16.5.
Specimen 2B E19.5: embryonic day 19.5 (more )
Structure Level Pattern Image Note
TS26: urothelium of bladder Present 2B E19.5 p63 (4A4)
Specimen 2B 6 hours: postnatal newborn (more )
Note: 6 hours after birth.
Structure Level Pattern Image Note
TS27: urothelium of bladder Present 2B 6 hours p63 (4A4)
Specimen 2B 24 hours: postnatal day 1 (more )
Note: 24 hours after birth.
Structure Level Pattern Image Note
TS27: urothelium of bladder Present 2B 24 hours p63 (4A4)
Specimen 2B 2 days: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: urothelium of bladder Present 2B 2 days p63 (4A4)
Specimen 2B 5 days: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: urothelium of bladder Present 2B 5 days p63 (4A4)
Specimen 2B 7 days: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: urothelium of bladder Present 2B 7 days p63 (4A4)
Specimen 2B 14 days: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: urothelium of bladder Present 2B 14 days p63 (4A4)
Specimen 3A wild type: embryonic day 18.5 (more )
Note: Double labeled: red - Trp63; green - Krt18 (assay MGI:5476995).
Structure Level Pattern Image Note
TS26: urothelium of bladder Present Regionally restricted 3A wild type p63 (4A4) , 3A wild type merge Expression was detected in the basal and intermediate layers, but not in the umbrella cells.
Specimen 3A p63-null: embryonic day 18.5; Trp63tm2Brd/Trp63tm2Brd (more )
Note: Double labeled: red - Trp63; green - Krt18 (assay MGI:5476995).
Structure Level Pattern Image Note
TS26: urothelium of bladder Absent 3A p63-null merge , 3A p63-null p63 (4A4)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory