Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Scx-cre)HShuk
Name:	transgene insertion H, Chisa Shukunami
MGI ID:	MGI:5476830
Synonyms:	ScxCre-H
Transgene:	Tg(Scx-cre)HShuk  Location: unknown
Alliance:	Tg(Scx-cre)HShuk page

Strain of Origin:

(C57BL/6 x C3H)F1

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Scx-cre)HShuk expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Scx (MGI:102934)   Mutation details: A construct was generated with the cre recombinase sequence under control of approximately 11 kb of the Scx regulatory region (~4 kb of upstream sequence and ~5 kb of downstream sequence, retrieved from a bacterial artificial chromosome RP23-415D19). This construct was used to produce transgenic animals. Two lines were established with low transgene copy number (L) and high copy number (H). When lines were bred to reporter mice, cre activity was detected overlapping various Scx-positive expression domains including chondrogenic, tendonogenic and ligamentogenic regions, as well as in the lung, kidney and testes. (J:195053)

Activity:	Tissue activity of this recombinase allele
Driver:	Scx (mouse) Summary of all recombinase alleles driven by Scx. Comparative matrix view of recombinase activities Alliance mouse Scx gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:195053 Sugimoto Y, et al., Generation and characterization of ScxCre transgenic mice. Genesis. 2013 Apr;51(4):275-83
All:	3 reference(s)