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Gene Expression Data
Assay Details
Assay
Reference: J:180706 Gruber R, et al., MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway. Nat Cell Biol. 2011 Nov;13(11):1325-34
Assay type: RNA in situ
MGI Accession ID: MGI:5476820
Gene symbol: Mcph1
Gene name: microcephaly, primary autosomal recessive 1
Probe: Mcph1 cDNA1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen S1a/b & c: embryonic day 13.5 (more )
Note: a/b - brightfield/darkfield; c - higher magnification.
Structure Level Pattern Image Note
TS21: telencephalon Present Regionally restricted S1c , S1a/b Expression was detected in the walls of the lateral ventricles.
TS21: cerebral cortex subventricular zone Present S1c , S1a/b
TS21: cerebral cortex ventricular layer Present S1c , S1a/b
Specimen S1d/e & f: embryonic day 15.5 (more )
Note: d/e - brightfield/darkfield; f - higher magnification.
Structure Level Pattern Image Note
TS23: brain ventricular layer Present S1f , S1d/e
TS23: cerebral cortex subventricular zone Present S1f , S1d/e
TS23: cerebral cortex ventricular layer Present S1f , S1d/e
Specimen S1g/h & i: postnatal day 0 (more )
Note: g/h - brightfield/darkfield; i - higher magnification.
Structure Level Pattern Image Note
TS27: cerebral cortex subventricular zone Absent S1i , S1g/h
TS27: cerebral cortex ventricular zone Absent S1i , S1g/h
TS27: hippocampus Present S1i , S1g/h
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory