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Gene Expression Data
Assay Details
Assay
Reference: J:1784 Suzuki HR, et al., Localization of HstI transcripts to the apical ectodermal ridge in the mouse embryo. Dev Biol. 1992 Mar;150(1):219-22
Assay type: RNA in situ
MGI Accession ID: MGI:5476533
Gene symbol: Fgf4
Gene name: fibroblast growth factor 4
Probe: Fgf4 cDNA1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: In the figure only hindlimbs were shown. The same expression pattern was also seen in forelimbs.
Results
Specimen 3: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present Widespread 3 Expressed in all regions, although clearer in the posterior half.
TS19: myotome Weak Regionally restricted 3 Expressed in a subset of cells.

Specimen 4: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present Widespread 4 Expressed in all regions, although clearer in the posterior half.
TS19: hindlimb bud ectoderm Present Regionally restricted 4 Only expressed in apical ectodermal ridge.
TS19: hindlimb bud mesenchyme Absent 4 No expression in limb mesoderm.

Specimen not shown: embryonic day 8.0 (more )
Note: Samples are cross and sagittal sections of the embryo.
Structure Level Pattern Image Note
TS12: embryo Absent

Specimen not shown: embryonic day 9.0 (more )
Note: Samples are cross and sagittal sections of the embryo.
Structure Level Pattern Image Note
TS14: embryo Absent
TS14: limb Absent

Specimen not shown: embryonic day 10.0 (more )
Note: Samples are mid-sagittal sections of the embryo.
Structure Level Pattern Image Note
TS16: embryo Absent
TS16: limb Absent

Specimen not shown: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: apical ectodermal ridge Present Widespread Expressed in all regions, although clearer in the posterior half.
TS18: limb ectoderm Present Regionally restricted Only expressed in apical ectodermal ridge.
TS18: limb mesenchyme Absent

Specimen not shown: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: foot Present Regionally restricted Expressed in the apical ectodermal ridge.
TS20: hand Present Regionally restricted Expressed in the apical ectodermal ridge.

Specimen not shown: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: limb Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory