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Gene Expression Data
Assay Details
Assay
Reference: J:65419 Ito T, et al., Repulsive axon guidance molecule Sema3A inhibits branching morphogenesis of fetal mouse lung. Mech Dev. 2000 Oct;97(1-2):35-45
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5475114
Gene symbol: Sema3a
Gene name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
Antibody: Anti-Sema3a
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to fluorescein
Results
Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung epithelium Weak
Specimen 1A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lobar bronchus epithelium Strong Regionally restricted 1A Strong expression was detected in the lobar bronchus terminal epithelium. Weak expression was detected in the large airway epithelial cells.
Specimen 1C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: bronchiole epithelium Present 1C
TS26: alveolar system Present Regionally restricted 1C Expression was detected in the alveolar epithelium.
TS26: lung vascular element Weak Regionally restricted 1C A slight but significant expression was detected in endothelial cells of bronchiolar arteries.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory