About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:188372 Zhou M, et al., Tissue-specific and nutrient regulation of the branched-chain alpha-keto acid dehydrogenase phosphatase, protein phosphatase 2Cm (PP2Cm). J Biol Chem. 2012 Jul 6;287(28):23397-406
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5475103
Gene symbol: Ppm1k
Gene name: protein phosphatase 1K (PP2C domain containing)
Reporter: lacZ
Direct Detection
Results
Specimen 1D KO Brain: postnatal adult; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: brain Strong Regionally restricted 1D KO Brain High expression in neuronal cells.

Specimen 1D KO Heart: postnatal adult; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Strong 1D KO Heart

Specimen 1D KO Skeletal Muscle: postnatal adult; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: skeletal muscle Trace 1D KO Skeletal Muscle Very low expression.

Specimen 1D KO Pancreas: postnatal adult; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: pancreas Absent 1D KO Pancreas

Specimen 1D KO Lung: postnatal adult; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: bronchus smooth muscle Strong 1D KO Lung

Specimen 1D KO Spleen: postnatal adult; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: spleen Absent 1D KO Spleen

Specimen 1D KO Liver: postnatal adult; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: liver Strong Regionally restricted 1D KO Liver Expressed in hepatocytes.

Specimen 1D KO Diaphragm: postnatal adult; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: diaphragm Strong Regionally restricted 1D KO Diaphragm Expressed in myocytes.

Specimen 2A KO: embryonic day 10.5; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Note: Fixed in 0.2% glutaraldehyde, 0.02% Nonidet P-40, and 0.1% paraformaldehyde.
Structure Level Pattern Image Note
TS17: brain Present 2A KO
TS17: heart Present 2A KO

Specimen 2B: embryonic day 14.5; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS22: brain Present 2B embryo , 2B Brain
TS22: choroid plexus Strong 2B Brain , 2B embryo
TS22: heart Present 2B Heart , 2B embryo
TS22: liver Present 2B Liver , 2B embryo

Specimen 2C KO 0 day Heart: postnatal day 0; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS27: heart Present 2C KO 0 day Heart

Specimen 2C KO 0 day Brain: postnatal day 0; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS27: brain Present 2C KO 0 day Brain

Specimen 2C KO 0 day Liver: postnatal day 0; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS27: liver Present 2C KO 0 day Liver

Specimen 2C KO 0 day Skeletal Muscle: postnatal day 0; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS27: skeletal muscle Absent 2C KO 0 day Skeletal Muscle

Specimen 2C KO 7 day Heart: postnatal day 7; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: heart Present 2C KO 7 day Heart

Specimen 2C KO 7 day Brain: postnatal day 7; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: brain Present 2C KO 7 day Brain

Specimen 2C KO 7 day Liver: postnatal day 7; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: liver Present 2C KO 7 day Liver

Specimen 2C KO 7 day Skeletal Muscle: postnatal day 7; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: skeletal muscle Absent 2C KO 7 day Skeletal Muscle

Specimen 2C KO 28 day Heart: postnatal day 28; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: heart Present 2C KO 28 day Heart

Specimen 2C KO 28 day Brian: postnatal day 28; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: brain Present 2C KO 28 day Brain

Specimen 2C KO 28 day Liver: postnatal day 28; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: liver Present 2C KO 28 day Liver

Specimen 2C KO 28 day Skeletal Muscle: postnatal day 28; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: skeletal muscle Absent 2C KO 28 day Skeletal Muscle

Specimen S2 KO 0 day Lung: postnatal day 0; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS27: lung Absent S2_KO 0 day Lung

Specimen S2 KO 0 day Spleen: postnatal day 0; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS27: spleen Absent S2_KO 0 day Spleen

Specimen S2 KO 0 day Pancreas: postnatal day 0; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS27: pancreas Absent S2_KO 0 day Pancreas

Specimen S2 KO 7 day Lung: postnatal day 7; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: lung Absent S2_KO 7 day Lung

Specimen S2 KO 7 day Spleen: postnatal day 7; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: spleen Absent S2_KO 7 day Spleen

Specimen S2 KO 7 day Pancreas: postnatal day 7; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: pancreas Absent S2_KO 7 day Pancreas

Specimen S2 KO 28 day Lung: postnatal day 28; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: lung Absent S2_KO 28 day Lung

Specimen S2 KO 28 day Spleen: postnatal day 28; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: spleen Absent S2_KO 28 day Spleen

Specimen S2 KO 28 day Pancreas: postnatal day 28; Ppm1ktm1Yiwa/Ppm1ktm1Yiwa (more )
Structure Level Pattern Image Note
TS28: pancreas Absent S2_KO 28 day Pancreas


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory