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Emv72 Other Genome Feature Detail
Summary
  • Symbol
    Emv72
  • Name
    endogenous ecotropic MuLV 72
  • Synonyms
    Gp70
  • Feature Type
    endogenous retroviral region
  • IDs
    MGI:5474594
Location &
Maps
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  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 5, Syntenic
Strain
Comparison
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Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
When this insertion site is present, mice exhibit increased development of tumors from injected CT26 cells and decreased anti-tumor cytotoxic activity.
References
more
  • Summaries
    All 2
    Phenotypes 2
  • Earliest
    J:194735 McWilliams JA, et al., Age-dependent tolerance to an endogenous tumor-associated antigen. Vaccine. 2008 Mar 28;26(15):1863-73
  • Latest
    J:194383 Buhrman JD, et al., Augmenting antitumor T-cell responses to mimotope vaccination by boosting with native tumor antigens. Cancer Res. 2013 Jan 1;73(1):74-85
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory