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Gene Expression Data
Assay Details
Assay
Reference: J:131397 Cho KW, et al., Expression of phosphorylated forms of ERK, MEK, PTEN and PI3K in mouse oral development. Gene Expr Patterns. 2008 Apr;8(4):284-290
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5474093
Gene symbol: Map2k1
Gene name: mitogen-activated protein kinase kinase 1
Antibody: Phospho-MEK1/2 (Ser217/221) (9121)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Antibody recognizes the phosphorylated form of both Map2k1 (MGI:1346866) and Map2k2 (MGI:1346867); both genes were annotated.
Results
Specimen not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: oral region Present Regionally restricted Expression in the developing submandibular gland
TS19: palatal shelf Present Expression in the putative palatal process.

Specimen 2A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: oral region Present Regionally restricted 2A Expression in oral epithelium and mesenchyme, especially oral mucosa.
TS21: oral epithelium Moderate 2A

Specimen 2B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf epithelium Strong 2B
TS21: palatal shelf mesenchyme Strong 2B

Specimen 2C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tongue epithelium Strong 2C
TS21: tongue mesenchyme Strong 2C

Specimen 2D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tooth Absent 2D

Specimen 2E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: oral region Present Regionally restricted 2E Expression in oral epithelium and mesenchyme, especially oral mucosa.
TS22: oral epithelium Present 2E

Specimen 2F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: palatal shelf Strong 2F

Specimen 2G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: tongue epithelium Strong 2G
TS22: tongue mesenchyme Strong 2G

Specimen 2H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: dental papilla Weak 2H
TS22: dental sac Weak 2H

Specimen 2I: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: oral region Present Regionally restricted 2I Expression in oral epithelium and mesenchyme, especially oral mucosa.
TS23: oral epithelium Present 2I

Specimen 2J: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: palatal shelf epithelium Present Regionally restricted 2J Stronger expression in oral epithelium than in the nasal palate epithelium.

Specimen 2K: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: tongue epithelium Weak 2K
TS23: tongue mesenchyme Weak 2K

Specimen 2L: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: dental papilla Weak 2L
TS23: dental sac Weak 2L
TS23: tooth epithelium Present Widespread 2L Expression throughout dental epithelium, including inner dental epithelium, stratum intermedium, stellate reticulum and outer dental epithelium.
TS23: stellate reticulum Present 2L
TS23: stratum intermedium Present 2L

Specimen 2M: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: oral region Present Regionally restricted 2M Expression in oral epithelium and mesenchyme, especially the oral mucosa.

Specimen 2N: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: oral epithelium Present 2N

Specimen 2O: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: tongue epithelium Present 2O
TS24: tongue mesenchyme Present 2O
TS24: fungiform papillae Present Regionally restricted 2O No expression in the inner layer of the developing fungiform papilla.

Specimen 2P: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: tooth Present Widespread 2P
TS24: cervical loop Present Regionally restricted 2P Expression in cervical loop epithelium.
TS24: dental papilla Present 2P
TS24: dental sac Present 2P


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory