Gene Expression Data
Assay Details
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Assay
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Reference:
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J:47724
McMahon JA, et al., Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite. Genes Dev. 1998 May 15;12(10):1438-52
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5473677
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Gene symbol:
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Sim1
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Gene name:
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single-minded family bHLH transcription factor 1
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Results
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Specimen
8Q:
embryonic day 10.5; Nogtm1Amc/Nog +
(more  )
Specimen
8Q:
(close  )
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Genetic Background:
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either: 129 or (involves: 129S1/Sv * C57BL/6J)
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Mutant Allele(s):
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Nogtm1Amc/Nog+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: neural tube lateral wall |
Present |
Regionally restricted |
8Q
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Expression in differentiating motor neurons extending to hindlimb level.
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Specimen
8R:
(close )
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Genetic Background:
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either: 129/Sv or (involves: 129S1/Sv * C57BL/6J)
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Mutant Allele(s):
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Nogtm1Amc/Nogtm1Amc
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: neural tube lateral wall |
Absent |
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8R
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Authors state that motor neuron formation was completely absent at hindlimb levels.
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| TS17: somite |
Present |
Regionally restricted |
8R
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Expression extended into dorsomedial epithelial somite at level of hindlimb.
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Specimen
not shown:
(close )
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Genetic Background:
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either: 129/Sv or (involves: 129S1/Sv * C57BL/6J)
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Mutant Allele(s):
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Nogtm1Amc/Nogtm1Amc
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Analysis Tools