4933428M09Riktm1e(EUCOMM)Wtsi
Targeted Allele Detail
|
|
| Symbol: |
4933428M09Riktm1e(EUCOMM)Wtsi |
| Name: |
RIKEN cDNA 4933428M09 gene; targeted mutation 1e, Wellcome Trust Sanger Institute |
| MGI ID: |
MGI:5472756 |
| Gene: |
4933428M09Rik Location: ChrX:138079977-138081758 bp, + strand Genetic Position: ChrX, 61.27 cM, cytoband F1
|
| IMPC: |
4933428M09Rik gene page |
|
| Mutant Cell Lines: |
EPD0978_3_A10, EPD0978_3_A11, EPD0978_3_C12 |
| Germline Transmission: |
Unknown
|
| Parent Cell Line: |
JM8A3.N1 (ES Cell)
|
| Strain of Origin: |
C57BL/6N-Atm1Brd
|
| Project Collection: |
EUCOMM
|
|
| Allele Type: |
|
Targeted (Null/knockout, Reporter) |
| Mutation: |
|
Insertion
Vector: Ifitm2_intron_L1L2_GT1_LF2A_LacZ_BetactP_neo
|
| |
|
Mutation details: The Ifitm2_intron_L1L2_GT1_LF2A_LacZ_BetactP_neo cassette was inserted at position 138080345 of Chromosome X (Build GRCm39) within an endogenous exon, creating an artificial intron that splits the original exon into two artificial exons, where the downstream artificial exon is critical. The cassette is composed of the intron of the Ifitm2 gene containing an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other EUCOMMTOOLs alleles can be found at http://www.knockoutmouse.org/about/eucommtools/vectors.
(J:155845, J:173534)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 1 line available
|
| Carrying any 4933428M09Rik Mutation: |
7 strains or lines available
|
|
| Original: |
J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010; |
| All: |
2 reference(s) |
|
Analysis Tools
