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Gene Expression Data
Assay Details
Assay
Reference: J:176654 McCormick JA, et al., A SPAK Isoform Switch Modulates Renal Salt Transport and Blood Pressure. Cell Metab. 2011 Sep 7;14(3):352-64
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5472012
Gene symbol: Slc12a1
Gene name: solute carrier family 12, member 1
Antibody: NKCC2 antibody
Detection system: Secondary antibody
Results
Specimen 2A bottom, merge: postnatal (more )
Note: Double labeled: red - Slc12a1 (NKCC2); green - Stk39 (SPAK; assay MGI:5471843).
Structure Level Pattern Image Note
TS28: distal convoluted tubule Present 2A bottom merge , 2A NKCC2
TS28: loop of Henle distal straight tubule Present 2A bottom merge , 2A NKCC2
Specimen 6A, Wild Type, merge: postnatal (more )
Note: Double labeled: red - Slc12a1(NKCC2); green - Oxsr1 (assay MGI:5472074).
Structure Level Pattern Image Note
TS28: loop of Henle distal straight tubule Present 6A top merge , 6A NKCC2 Wild Type
Specimen 6A, Knockout, merge: postnatal; Stk39tm1Dlp/Stk39tm1Dlp (more )
Note: Double labeled: red - Slc12a1 (NKCC2); green - Oxsr1 (assay MGI:5472074).
Structure Level Pattern Image Note
TS28: loop of Henle distal straight tubule Present 6A bottom merge , 6A NKCC2 KO
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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