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Gene Expression Data
Assay Details
Assay
Reference: J:29941 Delorme B, et al., Developmental regulation of connexin 40 gene expression in mouse heart correlates with the differentiation of the conduction system. Dev Dyn. 1995 Dec;204(4):358-71
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5471921
Gene symbol: Gja5
Gene name: gap junction protein, alpha 5
Antibody: Anti-Cx40
Results
Specimen 6B: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS19: heart atrium Strong Regionally restricted 6B Expression was detected in the atrial trabeculations.
Specimen 6D: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: heart atrium Strong Regionally restricted 6D Expression was detected in the atrial trabeculations.
Specimen 6F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: heart atrium Present Regionally restricted 6F In the atrium expression is preferentially polarized to intercalated disks. The intensity of labeling decreased after birth, but it was still highly expressed in the adult.
Specimen not shown: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS19: atrioventricular canal Absent
TS19: heart left ventricle Present Regionally restricted Expression was slightly higher in the furthest left ventricle compared to the furthest right ventricle.
TS19: heart right ventricle Present Regionally restricted Expression was slightly higher in the furthest left ventricle compared to the furthest right ventricle.
Specimen 7B: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS19: heart ventricle Present Regionally restricted 7B Expression was high in the trabeculae.
TS19: interventricular septum Absent 7B
Specimen 7D: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS19: heart ventricle Present Regionally restricted 7D Expression was detected in the trabecular network, with stronger expression in the sub-endocardial trabeculae than in the sub-epicardial cells.
Specimen 8A: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: atrioventricular canal Absent 8A
Specimen 8C: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: heart ventricle Present Graded 8C Immunoreactivity decreases from the top of the sub-endocardial trabeculae to the sub-epicardial layers, which show very weak immunoreactivity.
Specimen 9B: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: heart ventricle Present Regionally restricted 9B Expression was detected in the trabeculae surrounding the interventricular septum, strongly on the right side.
Specimen 10: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: heart ventricle Present 10 Expression was detected in the trabeculae. Expression was absent from the ventricular wall except in the blood vessels.
TS24: blood vessel Present 10 Expression was detected in the blood vessel endothelial cells in the ventricular wall.
TS24: atrioventricular bundle Present 10
TS24: interventricular septum Absent 10
Specimen 11A: embryonic day 19.0 (more )
Structure Level Pattern Image Note
TS26: atrioventricular bundle Present Regionally restricted 11A Expression was detected in the His bundle at the top of the septum and its left and right branches extending on both sides along the septum.
TS26: heart ventricle Weak Regionally restricted 11A Expression was detected in the trabeculations. No expression was detected in the ventricular walls except in the blood vessels.
TS26: blood vessel Present Regionally restricted 11A Expression was detected in the endothelial cells of the blood vessels in the ventricular walls.
Specimen 12B: postnatal week 1 (more )
Structure Level Pattern Image Note
TS28: heart ventricle Absent 12B Expression was no longer detected in the trabeculae.
TS28: atrioventricular bundle Strong 12B Expression was strong in the His bundle and in the upper part of the right bundle branch.
TS28: interventricular septum Absent 12B
Specimen not shown: embryonic day 14.0 (more )
Note: Data was from Table 1.
Structure Level Pattern Image Note
TS22: atrioventricular bundle Present Non-Uniform Staining was weak in the His bundle and was positive in the bundle branches.
TS22: interventricular septum Absent
Specimen not shown: embryonic day 19.0 (more )
Note: Data was from Table 1.
Structure Level Pattern Image Note
TS26: heart atrium Present
TS26: interventricular septum Absent
Specimen not shown: postnatal week 1 (more )
Note: Data was from Table 1.
Structure Level Pattern Image Note
TS28: heart atrium Present
TS28: heart ventricle Absent
Specimen not shown: postnatal week 2 (more )
Note: Data was from Table 1.
Structure Level Pattern Image Note
TS28: heart atrium Present
TS28: heart ventricle Absent
TS28: interventricular septum Absent
TS28: atrioventricular bundle Present Expression was detected in the His bundle and the bundle branches.
Specimen not shown: postnatal week 3 (more )
Note: Data was from Table 1.
Structure Level Pattern Image Note
TS28: heart atrium Present
TS28: heart ventricle Absent
TS28: interventricular septum Absent
TS28: atrioventricular bundle Present Expression was detected in the His bundle and the bundle branches.
Specimen not shown: postnatal adult (more )
Note: Data was from Table 1.
Structure Level Pattern Image Note
TS28: atrioventricular bundle Present Expression was detected in the His bundle and the bundle branches.
TS28: purkinje fiber Present
TS28: heart ventricle Absent
TS28: interventricular septum Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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