Gene Expression Data
Assay Details
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Assay
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Reference:
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J:185600
Cota CD, et al., The ENU-induced cetus mutation reveals an essential role of the DNA helicase DDX11 for mesoderm development during early mouse embryogenesis. Dev Dyn. 2012 Aug;241(8):1249-59
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5470547
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Gene symbol:
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Meox1
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Gene name:
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mesenchyme homeobox 1
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Results
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Specimen
2C:
embryonic day 8.5
(more  )
Specimen
2C:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: somite |
Present |
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2C
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Expression was detected in somitic mesoderm.
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Specimen
2D:
embryonic day 8.5
(more )
Specimen
2D:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: somite |
Present |
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2D
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Expression was detected in somitic mesoderm.
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Specimen
2E:
(close )
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Genetic Background:
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involves: C3HeB/FeJ * C57BL/6J
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Mutant Allele(s):
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Ddx11cetus/Ddx11cetus
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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late developmental arrest
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: somite |
Absent |
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2E
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Most cetus embryos were devoid of somitic mesoderm.
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Specimen
2F:
(close )
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Genetic Background:
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involves: C3HeB/FeJ * C57BL/6J
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Mutant Allele(s):
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Ddx11cetus/Ddx11cetus
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: somite |
Absent |
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2F
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Most cetus embryos were devoid of somitic mesoderm.
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Specimen
2G:
(close )
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Genetic Background:
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involves: C3HeB/FeJ * C57BL/6J
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Mutant Allele(s):
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Ddx11cetus/Ddx11cetus
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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early developmental arrest
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: somite |
Absent |
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2G
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Most cetus embryos were devoid of somitic mesoderm.
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Specimen
2H:
(close )
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Genetic Background:
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involves: C3HeB/FeJ * C57BL/6J
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Mutant Allele(s):
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Ddx11cetus/Ddx11cetus
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: somite |
Absent |
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2H
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Most cetus embryos were devoid of somitic mesoderm.
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Specimen
5D:
embryonic day 8.5
(more )
Specimen
5D:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
5E:
(close )
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Genetic Background:
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involves: 129S/SvEv
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Mutant Allele(s):
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Ddx11tm1Jiml/Ddx11tm1Jiml
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: somite |
Absent |
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5E
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Mutants lack discernible somites.
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Specimen
7C:
embryonic day 8.5
(more )
Specimen
7C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
7D:
(close )
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Genetic Background:
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involves: C3HeB/FeJ * C57BL/6J * CAST/Ei
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Mutant Allele(s):
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Ddx11cetus/Ddx11cetus
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: paraxial mesenchyme |
Present |
Regionally restricted |
7D
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A small percentage of cetus mutants have small bilateral patches of expression in the anterior embryonic flanks, suggesting somitogenesis is initiated in some cases.
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Specimen
8A:
embryonic day 8.5
(more )
Specimen
8A:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
8B:
(close )
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Genetic Background:
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involves: C3HeB/FeJ * C57BL/6J * CAST/Ei
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Mutant Allele(s):
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Ddx11cetus/Ddx11cetus
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: paraxial mesenchyme |
Present |
Regionally restricted |
8B
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In the mutant, expressing cells were sparse and failed to organize into the spherical structures characteristic of epithelial somites.
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Analysis Tools