Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	B4gat1m1Ddg
Name:	beta-1,4-glucuronyltransferase 1; mutation 1, David D Ginty
MGI ID:	MGI:5470461
Synonyms:	B3gnt1M155T, Line 1157
Gene:	B4gat1  Location: Chr19:5088854-5091159 bp, + strand  Genetic Position: Chr19, 4.23 cM
Alliance:	B4gat1m1Ddg page

Strain of Origin:

C57BL/6

Allele Type:    Chemically induced (ENU) (Hypomorph) Mutation:    Single point mutation   Mutation details: ENU induced a T to C transversion in exon 1 in Line 1157 that results in a methionine to threonine (M155T) amino acid substitution in the catalytic domain. This allele is hypomorphic. (J:194150) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any B4gat1 Mutation:	18 strains or lines available

Original:	J:194150 Wright KM, et al., Dystroglycan organizes axon guidance cue localization and axonal pathfinding. Neuron. 2012 Dec 6;76(5):931-44
All:	2 reference(s)