Sfxn1<m1Mdf> Spontaneous Allele Detail MGI Mouse (MGI:5468013)

Sfxn1^m1Mdf
Spontaneous Allele Detail

Summary

Symbol:	Sfxn1^m1Mdf
Name:	sideroflexin 1; mutation 1, Mark Fleming
MGI ID:	MGI:5468013
Synonyms:	f
Gene:	Sfxn1 Location: Chr13:54225888-54262361 bp, + strand Genetic Position: Chr13, 28.4 cM
Alliance:	Sfxn1^m1Mdf page

Mutation
origin

Strain of Origin:

Not Specified

Mutation
description

Allele Type:		Spontaneous
Mutation:		Insertion
		Mutation details: An insertion of a single A residue after codon 15 of the reading frame. This mutation is predicted to result in a truncated protein consisting of the first 15 amino acids followed by 17 novel amino acids before an in-frame stop codon. (J:68377)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Sfxn1 Mutation:	41 strains or lines available

Notes

This allele is on of two suggested as responsible for the flexed tail mutation (f). J:128616 suggests that a Smad5 splicing defect (mutation in a polyT element in intron 4) may be causative of flexed tail.

References

Original:	J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015;
All:	3 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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