Slc1a2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:32068 Sutherland ML, et al., Glutamate transporter mRNA expression in proliferative zones of the developing and adult murine CNS. J Neurosci. 1996 Apr 1;16(7):2191-207
Assay type:	RNA in situ
MGI Accession ID:	MGI:5467992
Gene symbol:	Slc1a2
Gene name:	solute carrier family 1 (glial high affinity glutamate transporter), member 2

Probe:	Eaat2 oligo
Probe preparation:	Antisense labelled with S35 RNA
Visualized with:	Autoradiography

Results

3D ©

Specimen 3D: embryonic day 15.0 (more

)

Structure	Level	Image
TS23: inferior colliculus	Present	3D
TS23: superior colliculus	Present	3D
TS23: thalamus	Present	3D

3E ©

Specimen 3E: embryonic day 17.0 (more

)

Structure	Level	Image
TS25: inferior colliculus	Present	3E
TS25: superior colliculus	Present	3E
TS25: thalamus	Present	3E

3F ©

Specimen 3F: embryonic day 19.0 (more

)

Structure	Level	Image
TS26: inferior colliculus	Present	3F
TS26: superior colliculus	Present	3F
TS26: thalamus	Present	3F

4C ©

Specimen 4C: embryonic day 19.0 (more

)

Structure	Level	Pattern	Image	Note
TS26: ventral grey horn	Present		4C

5C ©

Specimen 5C: embryonic day 19.0 (more

)

Structure	Level	Pattern	Image	Note
TS26: olfactory cortex ventricular layer	Present		5C

5F ©

Specimen 5F: embryonic day 19.0 (more

)

Structure	Level	Pattern	Image	Note
TS26: hippocampus	Present		5F
TS26: telencephalon ventricular layer	Present		5F

5I ©

Specimen 5I: embryonic day 19.0 (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebellum	Present		5I
TS26: midbrain ventricular layer	Present		5I

6E ©

Specimen 6E: postnatal day 0 (more

)

Structure	Level	Pattern	Image
TS27: hippocampus	Present		6E
TS27: hypothalamus	Weak	Diffuse	6E
TS27: thalamus	Weak	Diffuse	6E
TS27: corpus callosum	Weak		6E
TS27: fimbria hippocampus	Weak		6E

6F ©

Specimen 6F: postnatal day 7 (more

)

Structure	Level	Image
TS28: cerebellar cortex	Strong	6F
TS28: forebrain	Strong	6F
TS28: accumbens nucleus	Present	6F
TS28: caudate-putamen	Present	6F
TS28: globus pallidus	Present	6F

6G ©

Specimen 6G: postnatal day 14 (more

)

Structure	Level	Pattern	Image	Note
TS28: forebrain	Strong		6G
TS28: cerebellar cortex	Strong		6G

6H ©

Specimen 6H: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: forebrain	Strong		6H
TS28: cerebellar cortex	Strong		6H

7C/D ©

Specimen 7C/D: postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: cerebral cortex	Present	Regionally restricted	7C/D	Expression is in the subventricular zone.

7G/H ©

Specimen 7G/H: postnatal day 14 (more

)

Structure	Level	Image	Note
TS28: cerebral cortex	Present	7G/H	Expression is in the subventricular zone.
TS28: cortical layer I	Present	7G/H
TS28: cortical layer II	Present	7G/H
TS28: cortical layer III	Strong	7G/H
TS28: cortical layer IV	Strong	7G/H
TS28: cortical layer V	Strong	7G/H

8A/B ©

Specimen 8A/B: postnatal day 14 (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Present	Regionally restricted	8A/B	Expression is in the subventricular zone.
TS28: cortical layer VI	Present		8A/B

8C/D ©

Specimen 8C/D: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Present	Regionally restricted	8C/D	Expression is in the subventricular zone.
TS28: cortical layer VI	Present		8C/D

9B/D ©

Specimen 9B/D: postnatal day 0 (more

)

Structure	Level	Image
TS27: dentate gyrus granule cell layer	Present	9B/D
TS27: dentate gyrus hilus	Present	9B/D
TS27: hippocampus pyramidal cell layer	Present	9B/D
TS27: hippocampus stratum lacunosum	Present	9B/D
TS27: hippocampus stratum oriens	Present	9B/D
TS27: hippocampus stratum radiatum	Present	9B/D

9F/H ©

Specimen 9F/H: postnatal day 14 (more

)

Structure	Level	Pattern	Image	Note
TS28: dentate gyrus hilus	Strong		9F/H
TS28: hippocampus stratum lacunosum	Strong		9F/H
TS28: hippocampus CA3	Strong	Regionally restricted	9F/H	Pyramidal cell layer.
TS28: hippocampus stratum oriens	Weak		9F/H

10B/D ©

Specimen 10B/D: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: dentate gyrus hilus	Strong	Regionally restricted	10B/D	Expression is in a single layer of hilar interneurons bordering the inner dentate granule cell layer.
TS28: hippocampus stratum lacunosum	Strong		10B/D
TS28: hippocampus stratum oriens	Strong		10B/D
TS28: dentate gyrus granule cell layer	Weak		10B/D

11F ©

Specimen 11F: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Weak		11F

12C/D ©

Specimen 12C/D: postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: corpus callosum	Present		12C/D

12E/F ©

Specimen 12E/F: postnatal day 14 (more

)

Structure	Level	Pattern	Image	Note
TS28: corpus callosum	Present		12E/F

12G/H ©

Specimen 12G/H: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: corpus callosum	Present		12G/H

Specimen Table 1 E15: embryonic day 15.0 (more

)

Structure	Level	Pattern	Image	Note
TS23: hippocampus	Strong
TS23: hypothalamus	Moderate
TS23: inferior colliculus	Moderate
TS23: medulla oblongata	Moderate
TS23: pons	Moderate
TS23: spinal cord	Moderate
TS23: superior colliculus	Moderate
TS23: thalamus	Moderate
TS23: cerebellum	Weak
TS23: cerebral cortex ventricular layer	Weak
TS23: olfactory lobe	Weak
TS23: telencephalon septum	Weak
TS23: cerebral cortex intermediate zone	Absent
TS23: midbrain ventricular layer	Absent

Specimen Table 1 E17: embryonic day 17.0 (more

)

Structure	Level	Pattern	Image	Note
TS25: hippocampus	Strong
TS25: cerebral cortex ventricular zone	Moderate
TS25: hypothalamus	Moderate
TS25: inferior colliculus	Moderate
TS25: medulla oblongata	Moderate
TS25: midbrain	Moderate
TS25: pons	Moderate
TS25: spinal cord	Moderate
TS25: superior colliculus	Moderate
TS25: telencephalon septum	Moderate
TS25: thalamus	Moderate
TS25: cerebellum	Weak
TS25: midbrain ventricular layer	Weak
TS25: olfactory lobe	Weak
TS25: cerebral cortex intermediate zone	Absent

Specimen Table 1 E19: embryonic day 19.0 (more

)

Structure	Level	Pattern	Image	Note
TS26: hippocampus	Strong
TS26: spinal cord	Strong
TS26: cerebral cortex ventricular zone	Moderate
TS26: hypothalamus	Moderate
TS26: inferior colliculus	Moderate
TS26: medulla oblongata	Moderate
TS26: midbrain	Moderate
TS26: pons	Moderate
TS26: superior colliculus	Moderate
TS26: thalamus	Moderate
TS26: cerebellum	Weak
TS26: midbrain ventricular layer	Weak
TS26: olfactory lobe	Weak
TS26: telencephalon septum	Weak
TS26: cerebral cortex intermediate zone	Absent

Specimen Table 2 1 Day: postnatal day 1 (more

)

Structure	Level	Pattern	Note
TS27: cerebral cortex	Moderate	Regionally restricted	Expression is in the lateral ventricular zone/subependymal zone.
TS27: corpus callosum	Moderate
TS27: dentate gyrus	Moderate
TS27: dentate gyrus hilus	Moderate
TS27: fimbria hippocampus	Moderate
TS27: hippocampus CA3	Moderate
TS27: cerebellum Purkinje cell layer	Weak
TS27: cerebellum internal granule cell layer	Weak
TS27: cortical layer II	Weak
TS27: cortical layer III	Weak
TS27: cortical layer IV	Weak
TS27: cortical layer V	Weak
TS27: cortical layer VI	Weak
TS27: entorhinal cortex	Weak
TS27: hippocampus CA1	Weak
TS27: hippocampus CA2	Weak
TS27: hippocampus stratum lacunosum	Weak
TS27: hippocampus stratum oriens	Weak
TS27: hippocampus stratum radiatum	Weak
TS27: inferior colliculus	Weak
TS27: medial habenular nucleus	Weak
TS27: presubiculum	Weak
TS27: superior colliculus	Weak
TS27: retrohippocampal cortex	Weak	Regionally restricted	Parasubiculum.
TS27: forebrain	Weak	Regionally restricted	Weak in the lateral septum.
TS27: accumbens nucleus	Absent
TS27: anterior dorsal thalamic nucleus	Absent
TS27: caudate-putamen	Absent
TS27: cerebellum external granule cell layer	Absent
TS27: cerebellum molecular layer	Absent
TS27: dorsal lateral geniculate nucleus	Absent
TS27: globus pallidus	Absent
TS27: hippocampus molecular layer	Absent
TS27: reticular thalamic nucleus	Absent
TS27: ventral lateral geniculate nucleus	Absent
TS27: ventral posterior medial thalamic nucleus	Absent

Specimen Table 2 7 Day: postnatal day 7 (more

)

Structure	Level	Pattern	Note
TS28: cortical layer III	Very strong
TS28: cortical layer IV	Very strong
TS28: cerebellum Purkinje cell layer	Strong
TS28: cortical layer II	Strong
TS28: dentate gyrus hilus	Strong
TS28: entorhinal cortex	Strong
TS28: hippocampus CA2	Strong
TS28: hippocampus CA3	Strong
TS28: accumbens nucleus	Moderate
TS28: caudate-putamen	Moderate
TS28: cortical layer V	Moderate
TS28: cortical layer VI	Moderate
TS28: dentate gyrus	Moderate
TS28: globus pallidus	Moderate
TS28: hippocampus CA1	Moderate
TS28: hippocampus molecular layer	Moderate
TS28: hippocampus stratum lacunosum	Moderate
TS28: inferior colliculus	Moderate
TS28: medial habenular nucleus	Moderate
TS28: presubiculum	Moderate
TS28: reticular thalamic nucleus	Moderate
TS28: superior colliculus	Moderate
TS28: ventral lateral geniculate nucleus	Moderate
TS28: ventral posterior medial thalamic nucleus	Moderate
TS28: cerebral cortex	Moderate	Regionally restricted	Expression is in the lateral ventricular zone/subependymal zone.
TS28: forebrain	Moderate	Regionally restricted	moderate in the triangular septum, weak in medial and lateral.
TS28: retrohippocampal cortex	Moderate	Regionally restricted	Parasubiculum.
TS28: anterior dorsal thalamic nucleus	Weak
TS28: cerebellum internal granule cell layer	Weak
TS28: cerebellum molecular layer	Weak
TS28: corpus callosum	Weak
TS28: dorsal lateral geniculate nucleus	Weak
TS28: fimbria hippocampus	Weak
TS28: hippocampus stratum oriens	Weak
TS28: hippocampus stratum radiatum	Weak
TS28: cerebellum external granule cell layer	Absent

Specimen Table 2 14 Day: postnatal day 14 (more

)

Structure	Level	Pattern	Note
TS28: cortical layer III	Very strong
TS28: cortical layer IV	Very strong
TS28: entorhinal cortex	Very strong
TS28: anterior dorsal thalamic nucleus	Strong
TS28: cerebellum Purkinje cell layer	Strong
TS28: cortical layer II	Strong
TS28: cortical layer V	Strong
TS28: cortical layer VI	Strong
TS28: dentate gyrus hilus	Strong
TS28: hippocampus CA2	Strong
TS28: hippocampus CA3	Strong
TS28: hippocampus molecular layer	Strong
TS28: hippocampus stratum lacunosum	Strong
TS28: inferior colliculus	Strong
TS28: medial habenular nucleus	Strong
TS28: presubiculum	Strong
TS28: cerebral cortex	Strong	Regionally restricted	Expression is in the lateral ventricular zone/subependymal zone.
TS28: retrohippocampal cortex	Strong	Regionally restricted	Parasubiculum.
TS28: accumbens nucleus	Moderate
TS28: caudate-putamen	Moderate
TS28: dentate gyrus	Moderate
TS28: dorsal lateral geniculate nucleus	Moderate
TS28: globus pallidus	Moderate
TS28: hippocampus CA1	Moderate
TS28: hippocampus stratum oriens	Moderate
TS28: hippocampus stratum radiatum	Moderate
TS28: reticular thalamic nucleus	Moderate
TS28: superior colliculus	Moderate
TS28: ventral lateral geniculate nucleus	Moderate
TS28: ventral posterior medial thalamic nucleus	Moderate
TS28: forebrain	Moderate	Regionally restricted	Expression is in the lateral, medial, and triangular septum.
TS28: cerebellum internal granule cell layer	Weak
TS28: cerebellum molecular layer	Weak
TS28: corpus callosum	Weak
TS28: fimbria hippocampus	Weak
TS28: cerebellum external granule cell layer	Absent

Specimen Table 2 Adult: postnatal adult (more

)

Structure	Level	Pattern	Note
TS28: entorhinal cortex	Very strong
TS28: cerebellum Purkinje cell layer	Strong
TS28: cortical layer II	Strong
TS28: cortical layer III	Strong
TS28: cortical layer IV	Strong
TS28: dentate gyrus hilus	Strong
TS28: hippocampus CA2	Strong
TS28: hippocampus CA3	Strong
TS28: hippocampus molecular layer	Strong
TS28: inferior colliculus	Strong
TS28: presubiculum	Strong
TS28: retrohippocampal cortex	Strong	Regionally restricted	Parasubiculum.
TS28: accumbens nucleus	Moderate
TS28: anterior dorsal thalamic nucleus	Moderate
TS28: caudate-putamen	Moderate
TS28: cortical layer V	Moderate
TS28: cortical layer VI	Moderate
TS28: dentate gyrus	Moderate
TS28: dorsal lateral geniculate nucleus	Moderate
TS28: globus pallidus	Moderate
TS28: hippocampus CA1	Moderate
TS28: hippocampus stratum lacunosum	Moderate
TS28: hippocampus stratum oriens	Moderate
TS28: hippocampus stratum radiatum	Moderate
TS28: medial habenular nucleus	Moderate
TS28: reticular thalamic nucleus	Moderate
TS28: superior colliculus	Moderate
TS28: ventral lateral geniculate nucleus	Moderate
TS28: ventral posterior medial thalamic nucleus	Moderate
TS28: cerebral cortex	Moderate	Regionally restricted	Expression is in the lateral ventricular zone/subependymal zone.
TS28: forebrain	Moderate	Regionally restricted	Expression is in the lateral, medial, and triangular septum.
TS28: cerebellum internal granule cell layer	Weak
TS28: cerebellum molecular layer	Weak
TS28: corpus callosum	Weak
TS28: fimbria hippocampus	Weak
TS28: cerebellum external granule cell layer	Absent

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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