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Gene Expression Data
Assay Details
Assay
Reference: J:60593 Millonig JH, et al., The mouse Dreher gene Lmx1a controls formation of the roof plate in the vertebrate CNS [see comments]. Nature. 2000 Feb 17;403(6771):764-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5467828
Gene symbol: Mafb
Gene name: MAF bZIP transcription factor B
Antibody: Anti-MafB
Results
Specimen 4c: embryonic day 9.75 (more )
Structure Level Pattern Image Note
TS16: future hindbrain roof plate Present 4c
TS16: future midbrain roof plate Present 4c
TS16: neural tube roof plate Present 4c
TS16: midbrain-hindbrain junction Present Regionally restricted 4c The roof plate was immunopositive at the mesencephalon/metencephalon border.

Specimen 4d: embryonic day 9.75; Lmx1adr-J/Lmx1adr-J (more )
Structure Level Pattern Image Note
TS16: future hindbrain Absent 4d
TS16: future midbrain Absent 4d
TS16: future spinal cord Absent 4d
TS16: midbrain-hindbrain junction Weak Regionally restricted 4d Expression was detected in a severely reduced roof plate at the anterior aspect of the mesencephalon/metencephalon region.

Specimen not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: central nervous system roof plate Present

Specimen not shown: embryonic day 11.5; Lmx1adr-J/Lmx1adr-J (more )
Structure Level Pattern Image Note
TS19: central nervous system roof plate Absent The roof plate was absent in the mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory