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Gene Expression Data
Assay Details
Assay
Reference: J:43464 Matise MP, et al., Expression patterns of developmental control genes in normal and Engrailed-1 mutant mouse spinal cord reveal early diversity in developing interneurons. J Neurosci. 1997 Oct 15;17(20):7805-16
Assay type: RNA in situ
MGI Accession ID: MGI:5467299
Gene symbol: Evx1
Gene name: even-skipped homeobox 1
Probe: probe 3
Probe preparation: Antisense RNA
Results
Specimen 1a: embryonic day 10.5; En1tm2Alj/En1+ (more )
Note: Double labeled: purple - Evx1; blue - En1 reporter (assay MGI:5467409)
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 1a Expression was detected in the ventral intermediate zone. Expressing cells were in a cluster located dorsal to and not overlapping with En1 expressing cells.
Specimen not shown: embryonic day 10.5; En1tm2Alj/En1+ (more )
Note: Also stained for En1 reporter (assay MGI:5467409)
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted The relationship of En1 to Evx1 expression was also seen in the hindbrain.
TS17: rhombomere 1 Absent
TS17: rhombomere 2 Present The rostral boundary of expression was at the border of rhombomeres 1 and 2.
Specimen not shown: embryonic day 11.5; En1tm2Alj/En1+ (more )
Note: Also stained for En1 reporter (assay MGI:5467409)
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted The relationship of En1 to Evx1 expression was also seen at E11.5.
TS19: hindbrain Present Regionally restricted The relationship of En1 to Evx1 expression was also seen at E11.5.
Specimen 1c: embryonic day 10.5 (more )
Note: Also stained for Lmx1b (assay MGI:5467415); both purple.
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 1c Expressing cells were separated from the more dorsal Lmx1b-expressing cells by a gap.
Specimen 8a: embryonic day 10.5; En1tm2Alj/En1tm2Alj (more )
Note: Double labeled: purple - Evx1; blue - En1 reporter (assay MGI:5467409)
Structure Level Pattern Image Note
TS17: future spinal cord Present 8a Normal expression was detected in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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