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Gene Expression Data
Assay Details
Assay
Reference: J:1430 Hutchins JB, et al., Developmental distribution of platelet-derived growth factor in the mouse central nervous system. Brain Res Dev Brain Res. 1992 Jun 19;67(2):121-35
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5467255
Gene symbol: Pdgfa
Gene name: platelet derived growth factor, alpha
Antibody: anti-PDGF(AA)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: The antibody used in this assay recognizes the alpha chain, whether it is in a hetero- or homodimer.
Results
Specimen 2: embryonic day 11.5 (more )
Note: parasagittal section
Structure Level Pattern Image Note
TS19: telencephalon ventricular layer Strong Widespread 2A
TS19: telencephalon mantle layer Present Regionally restricted 2B , 2A Expression is present in the intermediate zone of the developing corpus striatum in structures similar to growth cones.
Specimen 3A: embryonic day 12.5 (more )
Note: transverse section
Structure Level Pattern Image Note
TS20: basal columns Present Regionally restricted 3B , 3A Expression is present in the future ventral horn.
Specimen 4A: embryonic day 13.5 (more )
Note: parasagittal section
Structure Level Pattern Image Note
TS21: basal columns Present Regionally restricted 4A Expression is present in the ventral spinal cord.
TS21: dorsal root ganglion Present Widespread 4A , 4B
TS21: spinal nerve Ambiguous 4A Little expression is seen in the nerve coursing distal to the dorsal root ganglion.
Specimen 5B: embryonic day 13.5 (more )
Note: parasagittal section
Structure Level Pattern Image Note
TS21: trigeminal ganglion Present Single cells 5B Little expression is seen at this stage.
Specimen 6D: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: trigeminal ganglion Present Single cells 6D Expression is present in only a few cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory