About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:170250 Ando T, et al., The floor plate is sufficient for development of the sclerotome and spine without the notochord. Mech Dev. 2011 Jan-Feb;128(1-2):129-40
Assay type: RNA in situ
MGI Accession ID: MGI:5466706
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe80
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen not shown: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: notochord Present
Specimen not shown: embryonic day 8.5; Etn2Sd/Etn2+ (more )
Structure Level Pattern Image Note
TS13: notochord Present
Specimen not shown: embryonic day 8.5; Etl4Gt(pU8)80211Imeg/Etl4+, Etn2Sd/Etn2+ (more )
Structure Level Pattern Image Note
TS13: notochord Present
Specimen not shown: embryonic day 8.5; Etl4Gt(pU8)80211Imeg/Etl4Gt(pU8)80211Imeg, Etn2Sd/Etn2+ (more )
Structure Level Pattern Image Note
TS13: notochord Present
Specimen not shown: embryonic day 8.5; Etn2Sd/Etn2Sd (more )
Structure Level Pattern Image Note
TS13: notochord Present
Specimen not shown: embryonic day 8.5; Etl4Gt(pU8)80211Imeg/Etl4Gt(pU8)80211Imeg, Etn2Sd/Etn2Sd (more )
Structure Level Pattern Image Note
TS13: notochord Present
Specimen 6A: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: floor plate Present 6A
TS14: forelimb bud Present 6A
TS14: future brain Present 6A
TS14: gut Present 6A
TS14: notochord Present 6A
Specimen 6B: embryonic day 9.0; Etn2Sd/Etn2+ (more )
Structure Level Pattern Image Note
TS14: floor plate Present 6B Expression similar to that of wild type embryos.
TS14: forelimb bud Present 6B Expression similar to that of wild type embryos.
TS14: future brain Present 6B Expression similar to that of wild type embryos.
TS14: gut Present 6B Expression similar to that of wild type embryos.
TS14: notochord Present 6B Expression similar to that of wild type embryos.
Specimen 6C: embryonic day 9.0; Etl4Gt(pU8)80211Imeg/Etl4+, Etn2Sd/Etn2+ (more )
Structure Level Pattern Image Note
TS14: floor plate Present 6C Expression similar to that of wild type embryos.
TS14: forelimb bud Present 6C Expression similar to that of wild type embryos.
TS14: future brain Present 6C Expression similar to that of wild type embryos.
TS14: gut Present 6C Expression similar to that of wild type embryos.
TS14: notochord Present 6C Expression similar to that of wild type embryos.
Specimen 6D: embryonic day 9.0; Etl4Gt(pU8)80211Imeg/Etl4Gt(pU8)80211Imeg, Etn2Sd/Etn2+ (more )
Structure Level Pattern Image Note
TS14: floor plate Present 6D Expression similar to that of wild type embryos.
TS14: forelimb bud Present 6D Expression similar to that of wild type embryos.
TS14: future brain Present 6D Expression similar to that of wild type embryos.
TS14: gut Present 6D Expression similar to that of wild type embryos.
TS14: notochord Present 6D Expression similar to that of wild type embryos.
Specimen 6E: embryonic day 9.0; Etn2Sd/Etn2Sd (more )
Structure Level Pattern Image Note
TS14: neural tube floor plate Present Regionally restricted 6E Expression disappeared below level of somite 18.
Specimen 6F: embryonic day 9.0; Etl4Gt(pU8)80211Imeg/Etl4Gt(pU8)80211Imeg, Etn2Sd/Etn2Sd (more )
Structure Level Pattern Image Note
TS14: neural tube floor plate Present Regionally restricted 6F Expression disappeared below level of somite 17.
Specimen 6G: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: floor plate Present 6G
TS16: gut Present 6G
TS16: limb Present 6G
TS16: notochord Present 6G
Specimen 6H: embryonic day 10.0; Etn2Sd/Etn2+ (more )
Structure Level Pattern Image Note
TS16: floor plate Present Widespread 6H Expression along entire length of embryo.
Specimen 6I: embryonic day 10.0; Etl4Gt(pU8)80211Imeg/Etl4+, Etn2Sd/Etn2+ (more )
Structure Level Pattern Image Note
TS16: neural tube floor plate Present Regionally restricted 6I Expression disappeared below level of somite 32.
Specimen 6J: embryonic day 10.0; Etl4Gt(pU8)80211Imeg/Etl4Gt(pU8)80211Imeg, Etn2Sd/Etn2+ (more )
Structure Level Pattern Image Note
TS16: neural tube floor plate Present Regionally restricted 6J Expression disappeared below level of somite 30.
Specimen 6K: embryonic day 10.0; Etn2Sd/Etn2Sd (more )
Structure Level Pattern Image Note
TS16: neural tube floor plate Present Regionally restricted 6K Expression disappeard below level of somite 18.
Specimen 6L: embryonic day 10.0; Etl4Gt(pU8)80211Imeg/Etl4Gt(pU8)80211Imeg, Etn2Sd/Etn2Sd (more )
Structure Level Pattern Image Note
TS16: neural tube floor plate Present Regionally restricted 6L Expression disappeard below level of somite 18.
Specimen 6M: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: floor plate Present 6M
TS17: gut Present 6M
TS17: limb Present 6M
TS17: notochord Present 6M
Specimen 6N: embryonic day 10.5; Etn2Sd/Etn2+ (more )
Structure Level Pattern Image Note
TS17: floor plate Present Widespread 6N Expression along entire length of embryo.
Specimen 6O: embryonic day 10.5; Etl4Gt(pU8)80211Imeg/Etl4+, Etn2Sd/Etn2+ (more )
Structure Level Pattern Image Note
TS17: neural tube floor plate Present Regionally restricted 6O Expression disappeared below level of somite 32.
Specimen 6P: embryonic day 10.5; Etl4Gt(pU8)80211Imeg/Etl4Gt(pU8)80211Imeg, Etn2Sd/Etn2+ (more )
Structure Level Pattern Image Note
TS17: neural tube floor plate Present Regionally restricted 6P Expression disappeared below level of somite 30.
Specimen 6Q: embryonic day 10.5; Etn2Sd/Etn2Sd (more )
Structure Level Pattern Image Note
TS17: neural tube floor plate Present Regionally restricted 6Q Expression disappeared below level of somite 32.
Specimen 6R: embryonic day 10.5; Etl4Gt(pU8)80211Imeg/Etl4Gt(pU8)80211Imeg, Etn2Sd/Etn2Sd (more )
Structure Level Pattern Image Note
TS17: neural tube floor plate Present Regionally restricted 6R Expression disappeared below level of somite 30.
Specimen 6M": embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: notochord Present 6M"
TS17: neural tube floor plate Present 6M"
Specimen 6N": embryonic day 10.5; Etn2Sd/Etn2+ (more )
Structure Level Pattern Image Note
TS17: notochord Absent 6N"
TS17: neural tube floor plate Present 6N"
Specimen 6O": embryonic day 10.5; Etl4Gt(pU8)80211Imeg/Etl4+, Etn2Sd/Etn2+ (more )
Structure Level Pattern Image Note
TS17: notochord Absent 6O"
TS17: neural tube floor plate Present 6O"
Specimen 6P": embryonic day 10.5; Etl4Gt(pU8)80211Imeg/Etl4Gt(pU8)80211Imeg, Etn2Sd/Etn2+ (more )
Structure Level Pattern Image Note
TS17: notochord Absent 6P"
TS17: neural tube floor plate Present 6P"
Specimen 6Q": embryonic day 10.5; Etn2Sd/Etn2Sd (more )
Structure Level Pattern Image Note
TS17: notochord Absent 6Q"
TS17: neural tube floor plate Present 6Q"
Specimen 6R": embryonic day 10.5; Etl4Gt(pU8)80211Imeg/Etl4Gt(pU8)80211Imeg, Etn2Sd/Etn2Sd (more )
Structure Level Pattern Image Note
TS17: notochord Absent 6R"
TS17: neural tube floor plate Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory